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International Journal of Dentistry
Volume 2012, Article ID 465698, 6 pages
http://dx.doi.org/10.1155/2012/465698
Research Article

Effects of Forced Alcohol Intake Associated with Chronic Stress on the Severity of Periodontitis: An Animal Model Study

1Nucleus of Periodontal Research, University of Taubaté, 12020-340 Taubaté, SP, Brazil
2Dental School, University of Cuiabá, 78020-590 Cuiabá, MT, Brazil
3University of Cuiabá, 78020-590 Cuiabá, MT, Brazil
4Department of Periodontology, Federal University of Minas Gerais, 31270-901 Belo Herizonte, MG, Brazil

Received 27 June 2012; Revised 13 October 2012; Accepted 14 October 2012

Academic Editor: Isabela Almeida Pordeus

Copyright © 2012 Alessandra Nogueira Porto et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

This study histometrically evaluated the effect of forced alcohol intake by stressed animals on the severity of ligature-induced periodontitis in rats. Thirty-two rats were randomly divided in four groups: group GAL—alcohol and ligature; group GASL—alcohol, chronic physical stress, and ligature; GNC—negative control; GPC—positive control. GAL and GASL received 20% ethanol ad libitum, and GNC received water ad libitum for 60 days. After 24 hours of exposition to alcohol intake—by GAL and GASL—immobilization was applied as a chronic stressor in the GASL group for a two-month period, six times a week, in random hours. The means of the respective groups were statistically compared (Analysis of Variance and Tukey tests, ). The most severe periodontal breakdown was observed in nonstressed animals which drank alcohol (GAL), followed by stressed animals exposed to alcohol (GASL). GASL did not differ from the positive control group (GPC). The negative control group showed the lowest values of periodontal breakdown ( ). Conclusions. Non-stressed alcohol consumer animals showed the most severe pattern of periodontal breakdown. Although stressed animals which were forced to drink alcohol showed poorer periodontal status than the negative controls, their results were similar to those of positive controls.