International Journal of Dentistry

International Journal of Dentistry / 2012 / Article

Research Article | Open Access

Volume 2012 |Article ID 871532 | https://doi.org/10.1155/2012/871532

Veeratrishul Allareddy, Steven D. Vincent, John W. Hellstein, Fang Qian, Wendy R. K. Smoker, Axel Ruprecht, "Incidental Findings on Cone Beam Computed Tomography Images", International Journal of Dentistry, vol. 2012, Article ID 871532, 9 pages, 2012. https://doi.org/10.1155/2012/871532

Incidental Findings on Cone Beam Computed Tomography Images

Academic Editor: Yasuhiro Morimoto
Received29 Aug 2012
Revised15 Oct 2012
Accepted31 Oct 2012
Published10 Dec 2012

Abstract

Background. Cone beam computed tomography (CBCT) has gained widespread acceptance in dentistry for a variety of applications. Most dentists who are not radiologists/trained in radiology are generally not familiar with interpretation of anatomical structures and/or pathosis outside their area of primary interest, as often this was not within the scope of their training. Objectives. To assess that the number of incidental findings on a CBCT scan is high both within and outside of the primary area of interest, thereby emphasizing the importance of interpretation of all areas visualized on the scan. Materials and Methods. An oral and maxillofacial radiologist reviewed 1000 CBCT scans (382 males and 618 females) for findings both in- and outside the area of interest. Results. Of the 1000 subjects that were reviewed, 943 scans showed findings in the primary regions of interest and/or outside the regions of interest, and 76 different conditions were visualized in these scans both in and outside the areas of interest. Conclusion. From the wide scope of findings noted on these scans, it can be concluded that it is essential that a person trained in advanced interpretation techniques in radiology interprets cone beam computed tomography scans.

1. Introduction

The development of panoramic radiography in the 1950s and its commercial introduction in 1965 led to the widespread adoption and use of the technology. Although widely used, these images have the same inherent limitations as other 2D projections, namely, magnification and minification of structures, superimposition of anatomical and/or pathological entities, and misrepresentation of structures. However panoramic radiography is efficient at providing an overview of oral and maxillofacial hard tissues, including teeth, and may reveal associated pathoses of the jaws. To overcome some of the above limitations cone beam computed tomography (CBCT) for the jaws was developed in the 1990s and is gaining widespread acceptance in dentistry, especially in the last 5 years.

CBCT was initially developed for angiography and is also popularly used for radiotherapy guidance and mammography [1] as an alternative to conventional fan beam helical computed tomography (CT) machines to provide more rapid acquisition of a dataset of the entire field of view. This rapid acquisition has enabled less movement in patients during the process of acquisition of the images. In addition, the radiation dose to the patient is lower than that of conventional CT machines and CBCT machines are markedly less expensive than conventional CT machines.

However, there are disadvantages. The field of view is usually smaller than that of standard CT and there is a lack of differentiation among various soft tissues.

CBCT scanners were first introduced in 1997 in Italy [2]. Cone beam computed tomography scanners have been commercially available since 2001 in the United States [3].

CBCT is used in dentistry for a variety of applications such as(i)evaluation of pathosis in the jaws,(ii)evaluation of bone for implants,(iii)orthodontic assessments, (iv)tmj assessments, and(v)endodontic assessments.

This imaging modality is mainly for the osseous and dental components of the maxillofacial complex.

Most dentists who are not radiologists are not familiar with interpretation of anatomical structures and/or pathosis outside the area of primary interest. This study was undertaken to determine the prevalence and nature of unusual findings in and around the maxillofacial complex encountered in CBCT studies.

2. Aim

To assess whether the number of incidental findings on a CBCT scan is high inside and outside the primary areas of interest as well, thereby emphasizing the importance of interpretation of all areas visualized on the scan.

3. Materials and Methods

3.1. Source of the Scans

The CBCT scans (Table 2) used in the study were acquired on an i-CAT machine (Imaging Sciences International, Hatfield, PA). To assess the feasibility of this study, a pilot survey was carried out on a sequential series of 100 subjects scanned at a private imaging company. Institutional Review Board approval to use the information on the scans for the study was obtained at The University of Iowa. Once the data obtained from the initial 100 subjects showed the feasibility and importance of a comprehensive study, a series of 1000 subjects who were imaged at the same company were analyzed comprehensively. Consent was obtained from all the subjects as well as the private imaging company to use and share the information from the scan for purposes of education, including for teaching and research.

3.2. Field of View of the Scans

All the scans used for this study were acquired at a field of view of 13 cm and a 0.3 mm thickness.

3.3. Time of Exposure to Acquire the Scan

The time of exposure to acquire the scan was uniform at 8.5 seconds for 843 subjects and 20 seconds for 157 subjects after acquiring the scout image to assess and adjusted for proper positioning of the subject to include the region of interest in the scan. The field of view and thickness of the slices remained the same in both sets of subjects despite the change in scan time from 20 seconds to 8.5 seconds. The decrease in time of acquisition was due to the increased image acquisition speed of a new sensor. The field of view and the slice thickness remained the same for all the subjects.

3.4. Age and Sex Distribution of Subjects

The age range of subjects is 5 years and 11 to 87 years. See Table 1 for the entire list of ages of the subjects.


Age groupNumber of subjects
MalesFemalesTotal

5 years and 11 months–10121325
11–2078101179
21–30213051
31–40296291
41–505394147
51–6086134220
61–7064133197
71–80354479
81–874711

Total3826181000


Reason for ScanNo of Subjects

Implants/Bone evaluation for implants678
Impaction localization110
Orthodontic records67
Other possible pathosis46
Evaluation of graft in the sinuses area/bone assessment for implants40
Supernumerary teeth localization31
Sinus evaluation prior to implants17
TMJ assessment11

Total1000

3.5. Reasons for the Scan

The subjects scanned presented for a variety of reasons given in Table 1

3.6. Interpretation and Review of the Scans

An oral and maxillofacial radiologist (VA), using the proprietary i-CAT viewer software version 3.034, reviewed the images. If there was any doubt on any of the findings, other authors were consulted for their opinion.

4. Results

Table 3 represents the pathologic entities and/or anatomic variants found inside and out of the primary region of interest. For convenience they have been grouped into different headings in the table.


Findings VisualizedMaleFemaleTotal

Variations in size, shape, and number of teeth
 Oligodontia162238
 Supernumerary teeth191231
 Transposition235
 Compound Odontoma044
 Microdontia314
 Dentin dysplasia112
 Dentinogenesis imperfecta with osteogenesis imperfecta011
 Amelogenesis imperfecta101
 Taurodontism101
 Gemination101
 Macrodontia101

Periapical/parapical/peridental findings
 Rarefying osteitis114167281
 Enostosis5482136
 Graft material and sclerotic healing3573108
 Root fragments4555100
 Impactions (not including third molars)293766
 Restorative material in the periapical regions of teeth223759
 External resorption222042
 Sclerosing osteitis61117
 Oroantral fistulas6814
 Hypercementosis5813
 Cemento-osseous dysplasia1910
 Hyperplastic dental follicle358
 Fibrous dysplasia448
 Simple bone cyst347
 Residual cyst347
 Dentigerous cyst426
 Osteosclerosis235
 Cementoblastoma224
 Nasopalatine canal cyst303
 Reactive hyperplastic osteitis022
 Keratocystic odontogenic tumor112
 Giant cell lesion101
 Osteomyelitis112
 Radioosteonecrosis011
 Chemoosteonecrosis011

Pathosis/anatomical variants in the paranasal sinuses
 Mucositis/sinusitis/mucous retention pseudocysts246305551
 Surgical changes in the sinuses131629
 Hypoplastic sinuses81321
 Osteoma134

Findings in cervical vertebrae region
 Osteoarthrosis90150240
 Osseous screws in vertebrae123
 Fusion of C2-3 cervical vertebrae101
 Nonsegmentation of C2-3 vertebrae101

Findings in the TMJs region/associated structures
 Osteoarthrosis42116158
 Coronoid hyperplasia8917
 Condylar hyperplasia123
 Condylar hypoplasia202

Calcifications visualized in the volume
 Pineal gland calcifications43104147
 Tonsilliths533992
 Carotid artery calcifications282957
 Osteoma cutis91423
 Sialoliths134
 Vertebral artery calcification011

Other dystrophic calcifications
 Temporal regions123
 Adenoids112
 Epiglottis112

Other findings
 Adenoidal hyperplasia4463107
 Soft tissue swellings in the airway region279
 Palatal tori178
 Cleft palate415
 Shot gun wound044
 Hair artifacts044
 Hearing aids134
 Osteopenia134
 Retained suture material in the jaws224
 Nose ring033
 Earrings033
 Malignancy213
 Stafne defect213
 Mandibular hemihyperplasia202
 Unhealed fracture101
 Surgical drain in the soft tissue of brain101
 Surgical staples in the neck101
 Nut notch101
 Implant impinging on borders of the inferior alveolar canal101

Eighty nine subjects had variations in size, shape, and number of teeth. Amongst these subjects the most common finding was missing teeth (38 subjects). The other more common finding was the presence of supernumerary teeth (31 subjects) (Figure 1). Transposition (5 subjects), compound odontomas (Figure 2) (4 subjects), microdontia (4 subjects) were the other relatively common findings. It was interesting to note that rare entities like dentin dysplasia (2 subjects), dentinogenesis imperfecta (1 subject), amelogenesis imperfecta (1 subject) were encountered amongst the scans reviewed. Taurodontism (1 subject), gemination (1 subject), and macrodontia (1 subject) were the other conditions encountered amongst these patients as far as variations in shape and size of teeth were concerned.

The most common findings (783) were peridental in location. Periapical rarefying osteitis (281 subjects) was the most common finding followed by enostosis (136 subjects), graft material and/or sclerotic healing (108 subjects), retained root fragments both from deciduous and permanent teeth (100 subjects), impactions not including third molars (66 subjects), restorative material in the periapical regions of teeth (59 subjects), and external resorption (42 subjects). Relatively fewer common findings included sclerosing osteitis (17 subjects), oroantral fistula (14 subjects), hypercementosis (13 subjects), cemento-osseous dysplasia (Figure 3) (10 subjects), hyperplastic dental follicle (8 subjects), simple bone cyst (7 subjects), residual cyst (7 subjects), dentigerous cyst (Figure 4) (6 subjects), idiopathic osteosclerosis (5 subjects), cementoblastoma, (4 subjects), nasopalatine canal cyst (3 subjects) (Figure 5), reactive hyperplastic osteitis (2 subjects), keratocystic odontogenic tumor (2 subjects), osteomyelitis (2 subjects), and osteonecrosis both radiation induced (1 subject) and bisphosphonate induced (1 subjects).

The paranasal sinuses were the location of the next common findings (605 findings). Mucositis/sinusitis/mucus retention pseudocysts (grouped as one category) were the most common findings (551 subjects). Surgical changes (29 subjects), hypoplastic sinuses (21 subjects) and osteoma in one of the paranasal sinuses (4 subjects) were the other findings in the paranasal sinuses.

Osteoarthrosis (240 subjects) was the most common condition found in the cervical vertebrae. Osseous screws (3 subjects), fusion of cervical vertebrae (1 subject) and non-segmentation of C2-3 vertebrae (1 subject) were the other findings visualized in the vertebrae.

Osteoarthrosis (158 subjects) was also the most common condition found in the TMJs and associated structures. Coronoid hyperplasia (17 subjects), Condylar hyperplasia (3 subjects) and condylar hypoplasia (2 subjects) accounted for the other findings in the TMJs region.

Pineal gland calcifications (147 subjects), tonsilliths (92) subjects were the most common findings amongst the different calcifications seen. Carotid artery calcifications (Figure 6) (cervical and/or intracranial calcifications—57 subjects) were the most significant amongst the different calcifications visualized in these scans. Males (28 of the 382 subjects) had a significantly higher percentage of carotid artery calcifications when compared to females (29 of the 618 subjects). Osteoma cutis (23 subjects), sialoliths (4 subjects) and vertebral artery calcification (1 subjects), and a variety of dystrophic calcifications including in the temporal regions (3 subjects), adenoids (2 subjects), and epiglottis regions (2 subjects), were the other calcifications encountered in these scans.

There was a variety of other findings that were not grouped into any particular category in our study. Adenoidal hyperplasia (107 subjects) was the common other finding. There were also soft tissue swellings (9 subjects) in the airway regions other than in the adenoids. Large palatal tori (8 subjects), cleft palate (5 subjects), shot gun wound (4 subjects), hair artifacts (4 subjects), hearing aids (4 subjects), osteopenia (4 subjects), retained suture material in the jaws (4 subjects), nose rings (3 subjects), earrings (3 subjects), malignancy (3 subjects), Stafne defect (Figures 7(a) and 7(b)) (3 subjects), mandibular hemihyperplasia (Figure 8) (2 subjects), surgical drain in the soft tissue of the brain (1 subject), surgical staples in the neck (1 subject), nut notch (1 subject), and an implant impinging on the borders of the inferior alveolar canal (1 subject).

The most significant of all these findings were three malignancies (2 males and 1 female) found incidentally. One in the sella region had caused extensive destruction of the sella turcica (Figure 9), two subjects had metastatic lesions in the mandible, one from the prostate and one from breast (Figure 10).

5. Discussion

Of the 1000 scans that were reviewed only 57 had no osseous pathosis or incidental findings. 943 scans showed findings in the primary regions of interest and/or outside the regions of interest and 77 different conditions were visualized in these scans both in and outside the areas of interest. Often the scans had incidental findings in more than one area. The percent of incidental findings in our study (94.3) was similar to that of the the other studies done by Cağlayan and Tozoğlu [4] (92.8%) and Price et al. [5] [90.7%] and greater than the study by Cha et al. (24.5%) [6].

One of the advantages of the current study when compared to other studies like Price et al. is that in those subjects in whom there were diseases that were required following biopsy, the findings in the original report were compared with findings from the histopathological evaluation and the prevalence of the different diseases was based on the histopathological confirmation of the radiologic interpretation. This step the authors believe was the most significant when compared to other studies that evaluated incidental findings and had mentioned that this was one of the short comings of their study (Price et al.).

Our study is the largest study looking at incidental findings using 1000 subjects compared to the studies by Price et al. (300 cases), Cağlayan and Tozoğlu (207 cases), Cha et al. (500 cases), and Pette et al. [7] (318 cases). Such a large sample provides a better clarification of the importance of reviewing CBCT scans thoroughly as significant diseases such as malignancies and also those diseases that are relatively rare are more likely to be included in the sample size, for example, the malignancy cases which were the most significant and immediately life threatening to the subjects. Our study also compares well with current published manuscripts by Pliska et al. [8] and Rogers et al. [9] and Pazera et al. [10] which all looked at incidental findings on CBCTs made on orthodontic patients. The advantage of our study in comparison to the above studies is that there is a greater likelihood of finding diseases when a wider age group of patients was included.

Some of the drawbacks of our study were that a single oral and maxillofacial radiologist reviewed all the images predominantly, although others were available for consultation. One of the other drawbacks of our study was that it included almost one half times (382 males to 618 females) the number of female subjects when compared to the males. It makes comparison of prevalence of various diseases somewhat more difficult than if there were equal number of subjects.

6. Conclusions

From the wide and comprehensive scope of findings found inside and outside the primary areas of interest in the 1000 subjects, it can be concluded that it is essential that a person trained in advanced interpretation techniques in radiology interprets CBCT scans. It can also be concluded that these CBCT images need to be reviewed comprehensively.

Acknowledgment

The author acknowledge 360 Imaging, Atlanta.

References

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Copyright © 2012 Veeratrishul Allareddy et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


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