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International Journal of Dentistry
Volume 2013, Article ID 521547, 13 pages
Review Article

Surgical Approaches Based on Biological Objectives: GTR versus GBR Techniques

1Department of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy
2Foundation IRCCS Ca’ Granda Policlinic, Milan, Italy

Received 6 February 2013; Revised 30 March 2013; Accepted 19 May 2013

Academic Editor: Zvi Artzi

Copyright © 2013 Gaia Pellegrini et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Guided tissue regenerative (GTR) therapies are performed to regenerate the previously lost tooth supporting structure, thus maintaining the aesthetics and masticatory function of the available dentition. Alveolar ridge augmentation procedures (GBR) intend to regain the alveolar bone lost following tooth extraction and/or periodontal disease. Several biomaterials and surgical approaches have been proposed. In this paper we report biomaterials and surgical techniques used for periodontal and bone regenerative procedures. Particular attention will be adopted to highlight the biological basis for the different therapeutic approaches.