Review Article

The Efficacy of Strontium and Potassium Toothpastes in Treating Dentine Hypersensitivity: A Systematic Review

Table 3

Characteristics of the included Strontium containing toothpaste studies.

No.StudyMethodsParticipantsInterventionsOutcomesResults

1Minkoff and Axelrod [99]*12 weeks, parallel, double-blind, randomised57 completing out of 6110% SrCl2 versus 0% SrCl2Tactile and thermal
SrCl2 > placebo control (P < 0.05) after 4 weeks (subjective), after 8 weeks (air blast), and at 12 weeks (tactile)

Formulation was subsequently changed from an SrCl2 with diatomaceous earth to SrCl2 with a silica abrasive/filler. A Strontium chloride toothpaste is no longer available in some markets. A Strontium acetate with fluoride toothpaste is currently available.