Human Calmodulin-Like Protein CALML3: A Novel Marker for Normal Oral Squamous Mucosa That Is Downregulated in Malignant Transformation

Figure 4

Total stain scores in the superficial cellular compartments and the basal cellular compartments among the tissue categories of benign, dysplasia/carcinoma in situ, and invasive squamous cell carcinoma. A statistically significant trend is seen in CALML3 expression from benign mucosal cells to invasive squamous cell carcinoma. As disease severity increases, CALML3 expression decreases.