A New Weak Chelator in Endodontics: Effects of Different Irrigation Regimens with Etidronate on Root Dentin Microhardness

Table 2

Mean and standard deviation and 𝑃 values (Student’s t-test) for microhardness analysis in the middle third before (T0) and after (T1) the application of the irrigation regimens.

Groups	Middle third (MT)
	T0; X ± SD	T1; X ± SD	P value; (Student’s t-test)
G1: saline	46.9±5.1	45.1±3.7	0.43
G2: mixture 5% NaOCl and 18% HEBP (30 min)	45.5±5.5	35.7±4.1	0.006
G3: 2.5% NaOCl (30 min)	44.9±5.0	39.8±2.9	0.01
G4: 2.5% NaOCl (30 min) + 17% EDTA (3 min)	47.3±3.7	34.5±5.4	<0.001
G5: 2.5% NaOCl (30 min) + 10% CA (3 min)	45.2±3.5	31.4±7.4	<0.0001
G6: 2.5% NaOCl (30 min) + 9% HEBP (5 min)	47.7±4.6	42.6±3.0	0.02
G7: 2.5% NaOCl (30 min) + 17% EDTA (3 min) + 2.5% NaOCl (3 min)	47.3±3.7	34.4±5.4	<0.0001
G8: 2.5% NaOCl (30 min) + 10% CA (3 min) + 2.5% NaOCl (3 min)	45.6±2.9	29.8±6.4	<0.0001
G9: 2.5% NaOCl (30 min) + 9% HEBP (5 min) + 2.5% NaOCl (3 min)	47.7±4.6	41.8±4.2	0.004

X: mean; SD: standard deviation.