Clinical Study

Immunohistochemical Analysis of the Activation Status of the Akt/mTOR/pS6 Signaling Pathway in Oral Lichen Planus

Table 1

Percentage of positive cases and average positivity, intensity, and total scores for nuclear p-Akt per lesion category.

ā€‰Number and %
of positive cases
Average positivity
score
Average intensity
score
Average total
score

OLP37/40 (92.5%)2.001.533.53
NM9/9 (100%)1.781.783.56
OL17/17 (100%)2.94*2.71*5.65*
OSCC7/10 (70%)1.801.303.10

OLP: oral lichen planus; NM: normal mucosa; OL: oral leukoplakia; OSCC: oral squamous cell carcinoma.
*Statistical significant differences ( ), compared to OLP.