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International Journal of Dentistry
Volume 2015, Article ID 153284, 7 pages
Research Article

In Vitro Ability of a Novel Nanohydroxyapatite Oral Rinse to Occlude Dentine Tubules

1Dental Physical Sciences, Barts and The London School of Medicine and Dentistry, Queen Mary University of London (QMUL), London E1 4NS, UK
2School of Dentistry, The University of Manchester, Manchester M13 9PL, UK
3Centre for Adult Oral Health, Barts and The London School of Medicine and Dentistry, Queen Mary University of London (QMUL), London E1 2AD, UK

Received 19 January 2015; Revised 4 April 2015; Accepted 23 April 2015

Academic Editor: Patricia Pereira

Copyright © 2015 Robert G. Hill et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Objectives. The aim of the study was to investigate the ability of a novel nanohydroxyapatite (nHA) desensitizing oral rinse to occlude dentine tubules compared to selected commercially available desensitizing oral rinses. Methods. 25 caries-free extracted molars were sectioned into 1 mm thick dentine discs. The dentine discs () were etched with 6% citric acid for 2 minutes and rinsed with distilled water, prior to a 30-second application of test and control oral rinses. Evaluation was by (1) Scanning Electron Microscopy (SEM) of the dentine surface and (2) fluid flow measurements through a dentine disc. Results. Most of the oral rinses failed to adequately cover the dentine surface apart from the nHa oral rinse. However the hydroxyapatite, 1.4% potassium oxalate, and arginine/PVM/MA copolymer oral rinses, appeared to be relatively more effective than the nHA test and negative control rinses (potassium nitrate) in relation to a reduction in fluid flow measurements. Conclusions. Although the novel nHA oral rinse demonstrated the ability to occlude the dentine tubules and reduce the fluid flow measurements, some of the other oral rinses appeared to demonstrate a statistically significant reduction in fluid flow through the dentine disc, in particular the arginine/PVM/MA copolymer oral rinse.