Medication-Related Osteonecrosis of the Jaws: Considerations on a New Antiresorptive Therapy (Denosumab) and Treatment Outcome after a 13-Year Experience

Figure 2

At clinical examination, presence of postextractive necrotic bone exposure on the right mandible (a) of a female 51-year-old patient affected by breast cancer who underwent denosumab administration 9 times. Rx OPT confirms the presence of an area of bone alteration (b) which was diagnosed as stage III MRONJ accordingly with the dimensional staging systems and was surgically treated. After 12-month follow-up, clinical (c) and radiological (d) healing of the treated lesion without signs of recurrence is evident.

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