Experimentally Induced Pulpal Lesion and Substance P Expression: Effect of Ketoprofen—A Preliminary Study

Table 1

Substance P and pain evaluation after tooth extraction of upper third molars with experimentally induced pulpal lesion, in patients with ketoprofen administration 30 minutes before the procedure.

Patients group 1	SP pg/mg pulp	Appearance of pain; (hours after extraction)	Intensity of pain	Onset to pain relief; (minutes after ketoprofen intake)	Duration of pain; relief (hours)
1	158	7	Slight	No drug
2	125.75	6	Moderate	30	>5
3	140.58	6	Moderate	30	>5
4	40.65	6	Slight	No drug
5	88.9	7	Slight	30	>5
6	31.95	6	Slight	No drug
7	8,23	6	Moderate	No drug
8	72.53	6	Moderate	30	4-5
9	44.28	6	Slight	No drug
10	9.33	6	Moderate	30	3-4