Experimentally Induced Pulpal Lesion and Substance P Expression: Effect of Ketoprofen—A Preliminary Study

Table 2

Substance P and pain evaluation after tooth extraction of upper third molars with experimentally induced pulpal lesion, in patients with no drug administration before the procedure.

Patients group 2	SP pg/mg pulp	Appearance of pain; (hours after extraction)	Intensity of pain	Onset to pain relief; (minutes after ketoprofen intake)	Duration of pain; relief (hours)
1	121.57	3	Moderate	30	>5
2	187.57	4,5	Slight	30	>5
3	83.43	4	Moderate	30	3-4
4	93.44	5	Moderate	30	4-5
5	73.25	5	Slight	30	>5
6	93.11	3	Slight	30	3-4
7	100.93	4	Moderate	30	>5
8	83.4	3,5	Slight	30	>5
9	88.44	3,5	Slight	30	3-4
10	122.71	4	Intense	30	4-5