|
| Lesion | Gender predominance | Age predilection | Location | Shape of ulcer | Number of ulcers | Distinguishing features |
|
| Recurrent aphthous stomatitis | Women | Beginning at 2nd decade | Nonkeratinized mucosa in healthy patients | Symmetrical | Solitary/multiple | Prodromal burning, painful, round fibrin covered with erythematous borders, 3 clinical types: minor, major, herpetiform, self-limiting |
|
| Recurrent herpetic stomatitis | NA | NA | Keratinized mucosa especially hard palate in healthy patients | Scalloped borders | Multiple | Two subgroups: recurrent herpes simplex labialis, recurrent intraoral herpes, unilateral |
|
| Herpes-associated erythema multiform | Men | 20–40 years | Lips | Map-like | Multiple | Bullae and ulcerations with irregular borders and inflammatory halo, bloody encrustations on the lips |
|
| Cyclic neutropenia | NA | Begins in childhood | Any oral mucosa exposed to trauma | Aphthous-like | Multiple | Episodic ulcers with erythematous halo, concomitant fever, periodontitis, marked gingival recession, and systemic infections |
|
| Behçet’s disease | Balanced male/female ratio | Between the ages of 25 and 40 | Anywhere on the oral or pharyngeal mucosa | Aphthous-like | Multiple | Concomitant genital ulcers, ocular inflammation, and skin lesions |
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