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International Journal of Dentistry
Volume 2016, Article ID 9868421, 15 pages
Review Article

Erythritol Is More Effective Than Xylitol and Sorbitol in Managing Oral Health Endpoints

1Cargill R&D Centre Europe, Havenstraat 84, 1800 Vilvoorde, Belgium
2Institute of Dentistry, University of Turku, Lemminkäisenkatu 2, 20520 Turku, Finland
3Institute of Dentistry, Faculty of Medicine, University of Tartu, Raekoja Plats 6, 51003 Tartu, Estonia
4Equinox Scientific Services, 11-26520 Twp Road 512, Spruce Grove, AB, Canada T7Y 1G1
5Cargill Incorporated, 15407 McGinty Road West (MS-163), Wayzata, MN 55391, USA

Received 23 May 2016; Accepted 13 July 2016

Academic Editor: Athena Papas

Copyright © 2016 Peter de Cock et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Objective. To provide a comprehensive overview of published evidence on the impact of erythritol, a noncaloric polyol bulk sweetener, on oral health. Methods. A literature review was conducted regarding the potential effects of erythritol on dental plaque (biofilm), dental caries, and periodontal therapy. The efficacy of erythritol on oral health was compared with xylitol and sorbitol. Results. Erythritol effectively decreased weight of dental plaque and adherence of common streptococcal oral bacteria to tooth surfaces, inhibited growth and activity of associated bacteria like S. mutans, decreased expression of bacterial genes involved in sucrose metabolism, reduced the overall number of dental caries, and served as a suitable matrix for subgingival air-polishing to replace traditional root scaling. Conclusions. Important differences were reported in the effect of individual polyols on oral health. The current review provides evidence demonstrating better efficacy of erythritol compared to sorbitol and xylitol to maintain and improve oral health.