International Journal of Dentistry / 2016 / Article / Tab 3

Review Article

Erythritol Is More Effective Than Xylitol and Sorbitol in Managing Oral Health Endpoints

Table 3

Summary of periodontal studies on air-polishing with erythritol.

Study typeSubstance testedSubjects or strainAge (years)TreatmentResultsReference

Randomized, controlled, parallel-group 3-month clinical trialErythritolAdults39 ~55Subgingivally treated for 5 seconds with an air-polishing device using erythritol or standard supportive periodontal therapyNo differences in clinical outcomes between subgingival air-polishing with erythritol or traditional scaling except that patients tended to prefer air-polishing with erythritolHägi et al. (2013) [49]

Randomized, controlled, parallel-group 6-month clinical trialErythritolAdults 38~55Subgingival low abrasive erythritol powder using an air-polishing device or repeated scaling and root planing at study sitesBoth treatments produced significant reductions in bleeding on probing and probing pocket depth and increases in clinical attachment level; no statistically significant differences between the treatment groupsHägi et al. (2015) [54]

Randomized clinical trialErythritolAdults50~8-9Subgingival air-polishing with erythritol containing 0.3% chlorhexidine was compared to ultrasonic debridement at 3-month intervals for up to 12 monthsNo difference between the treatments with respect to the presence or absence of a probing depth and the frequencies of 6 microorganisms; erythritol-treated sites were less frequently positive for Aggregatibacter actinomycetemcomitans Air-polishing with erythritol was significantly better than ultrasonic debridement in terms of pain/discomfort perceptionMüller et al.(2014) [55]

In vitro antimicrobial and antibiofilm study using sandblasted titanium disksErythritolStaphylococcus aureus, Bacteroides fragilis, and Candida albicans2Air-polishing with 99.7% erythritol/0.3% chlorhexidine versus standard glycine powder Erythritol/chlorhexidine was significantly more effective than glycine in inhibiting the growth of all 3 strains, reducing the number of surviving cells following air-polishing (15–30% for glycine, 50% for erythritol/chlorhexidine) and reducing the biofilm produced by all 3 strainsDrago et al. (2014) [56]