Table of Contents Author Guidelines Submit a Manuscript
International Journal of Dentistry
Volume 2017, Article ID 1914073, 9 pages
https://doi.org/10.1155/2017/1914073
Review Article

Genetic Factors and the Risk of Periodontitis Development: Findings from a Systematic Review Composed of 13 Studies of Meta-Analysis with 71,531 Participants

1Laboratory of Analysis and Histological Processing (LAPHIS), Federal University of Piaui, Parnaiba, PI, Brazil
2Postgraduate Program in Biomedical Sciences, Federal University of Piaui, Parnaiba, PI, Brazil
3Postgraduate Program in Biotechnology, Federal University of Piaui, Parnaiba, PI, Brazil
4Postgraduate Program in Dentistry, Federal University of Piaui, Teresina, PI, Brazil

Correspondence should be addressed to Daniel Fernando Pereira Vasconcelos; rb.ude.ipfu@solecnocsav

Received 2 December 2016; Revised 28 February 2017; Accepted 30 March 2017; Published 26 April 2017

Academic Editor: Tommaso Lombardi

Copyright © 2017 Maélson Klever da Silva et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. A. Bascones-Martinez, P. Matesanz-Perez, M. Escribano-Bermejo, M.-Á. González-Moles, J. Bascones-Ilundain, and J.-H. Meurman, “Periodontal disease and diabetes-Review of the literature,” Medicina Oral, Patologia Oral y Cirugia Bucal, vol. 16, no. 6, pp. e722–e729, 2011. View at Publisher · View at Google Scholar · View at Scopus
  2. D. F. P. Vasconcelos, F. R. da Silva, and M. S. C. Pinto, “Decrease of pericytes is associated with ligature-induced periodontitis liver disease in rats,” Journal of Periodontology, pp. 1–14, 2016. View at Google Scholar
  3. E. Carramolino-Cuéllar, I. Tomás, and Y. Jiménez-Soriano, “Relationship between the oral cavity and cardiovascular diseases and metabolic syndrome,” Medicina Oral, Patologia Oral y Cirugia Bucal, vol. 19, no. 3, pp. e289–e294, 2014. View at Publisher · View at Google Scholar · View at Scopus
  4. N. Sultan and J. Rao, “Association between periodontal disease and bone mineral density in postmenopausal women: a cross sectional study,” Medicina Oral, Patologia Oral y Cirugia Bucal, vol. 16, no. 3, Article ID 17170, pp. e440–e447, 2011. View at Publisher · View at Google Scholar · View at Scopus
  5. F. Carinci, A. Palmieri, A. Girardi, F. Cura, and L. Scapoli, “Genetic risk assessment of periodontal disease in healthy patients,” Journal of Forensic Research, vol. 6, no. 260, article 2, 2015. View at Publisher · View at Google Scholar
  6. A. Stabholz, W. A. Soskolne, and L. Shapira, “Genetic and environmental risk factors for chronic periodontitis and aggressive periodontitis,” Periodontology 2000, vol. 53, no. 1, pp. 138–153, 2010. View at Publisher · View at Google Scholar · View at Scopus
  7. L. Chambrone, A. Ascarza, M.-E. Guerrero et al., “Association of -1082 interleukin-10 gene polymorphism in Peruvian adults with chronic periodontitis,” Medicina Oral, Patologia Oral y Cirugia Bucal, vol. 19, no. 6, Article ID 19823, pp. e569–e573, 2014. View at Publisher · View at Google Scholar · View at Scopus
  8. L. Jiang, H. Weng, M.-Y. Chen, C. Zhang, and X.-T. Zeng, “Association between cyclooxygenase-2 gene polymorphisms and risk of periodontitis: a meta-analysis involving 5653 individuals,” Molecular Biology Reports, vol. 41, no. 7, pp. 4795–4801, 2014. View at Publisher · View at Google Scholar · View at Scopus
  9. M. Navarrete, J. García, N. Dutzan et al., “Interferon-γ, interleukins-6 and -4, and factor XIII-A as indirect markers of the classical and alternative macrophage activation pathways in chronic periodontitis,” Journal of Periodontology, vol. 85, no. 5, pp. 751–760, 2014. View at Publisher · View at Google Scholar · View at Scopus
  10. G. G. Song and Y. H. Lee, “Associations between FCGR2A rs1801274, FCGR3A rs396991, FCGR3B NA1/NA2 polymorphisms and periodontitis: a meta-analysis,” Molecular Biology Reports, vol. 40, no. 8, pp. 4985–4993, 2013. View at Publisher · View at Google Scholar · View at Scopus
  11. H. Weng, Y. Yan, Y.-H. Jin, X.-Y. Meng, Y.-Y. Mo, and X.-T. Zeng, “Matrix metalloproteinase gene polymorphisms and periodontitis susceptibility: a meta-analysis involving 6,162 individuals,” Scientific Reports, vol. 6, Article ID 24812, 2016. View at Publisher · View at Google Scholar · View at Scopus
  12. R. Amirisetty, R. P. Patel, S. Das, J. Saraf, A. Jyothy, and A. Munshi, “Interleukin 1β (+3954, -511 and -31) polymorphism in chronic periodontitis patients from North India,” Acta Odontologica Scandinavica, vol. 73, no. 5, pp. 343–347, 2015. View at Publisher · View at Google Scholar · View at Scopus
  13. K. Divaris, K. L. Monda, K. E. North et al., “Exploring the genetic basis of chronic periodontitis: a genome-wide association study,” Human Molecular Genetics, vol. 22, no. 11, pp. 2312–2324, 2013. View at Publisher · View at Google Scholar · View at Scopus
  14. K. E. Lohmueller, C. L. Pearce, M. Pike, E. S. Lander, and J. N. Hirschhorn, “Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease,” Nature Genetics, vol. 33, no. 2, pp. 177–182, 2003. View at Publisher · View at Google Scholar · View at Scopus
  15. F. da Silva, A. Guimaraes-Vasconcelos, L. de-Carvalho-Franca et al., “Relationship between –889 C/T polymorphism in interleukin-1A gene and risk of chronic periodontitis: evidence from a meta-analysis with new published findings,” Medicina Oral, Patología Oral y Cirugia Bucal, vol. 22, no. 1, pp. e7–e14, 2017. View at Publisher · View at Google Scholar
  16. M.-Y. Shao, P. Huang, R. Cheng, and T. Hu, “Interleukin-6 polymorphisms modify the risk of periodontitis: a systematic review and meta-analysis,” Journal of Zhejiang University: Science B, vol. 10, no. 12, pp. 920–927, 2009. View at Publisher · View at Google Scholar · View at Scopus
  17. Y. Yan, H. Weng, Z.-H. Shen, L. Wu, and X.-T. Zeng, “Association between interleukin-4 gene -590 C/T, -33 C/T, and 70-base-pair polymorphisms and periodontitis susceptibility: a meta-analysis,” Journal of Periodontology, vol. 85, no. 11, pp. e354–e362, 2015. View at Publisher · View at Google Scholar · View at Scopus
  18. W. F. Wang, J. Shi, S. J. Chen, Y. M. Niu, and X. T. Zeng, “Interleukin1a899 (+ 4845) C→T polymorphism is not associated with aggressive periodontitis susceptibility: a metaanalysis based on 19 casecontrol studies,” Biomedical Reports, vol. 2, no. 3, pp. 378–383, 2014. View at Google Scholar
  19. X.-T. Zeng, D.-Y. Liu, J. S. W. Kwong, W.-D. Leng, L.-Y. Xia, and M. Mao, “Meta-analysis of association between interleukin-1β C-511T polymorphism and chronic periodontitis susceptibility,” Journal of Periodontology, vol. 86, no. 6, pp. 812–819, 2015. View at Publisher · View at Google Scholar · View at Scopus
  20. Y.-J. Chen, Y. Han, M. Mao, Y.-Q. Tan, W.-D. Leng, and X.-T. Zeng, “Interleukin-1β rs1143634 polymorphism andaggressive periodontitis susceptibility: a meta-analysis,” International Journal of Clinical and Experimental Medicine, vol. 8, no. 2, pp. 2308–2316, 2015. View at Google Scholar · View at Scopus
  21. L. Ma, W.-M. Chu, J. Zhu, Y.-N. Wu, and Z.-L. Wang, “Interleukin-1β (3953/4) C→T polymorphism increases the risk of chronic periodontitis in Asians: evidence from a meta-analysis of 20 case-control studies,” Archives of Medical Science, vol. 11, no. 2, pp. 267–273, 2015. View at Publisher · View at Google Scholar · View at Scopus
  22. G. G. Song, S. J. Choi, J. D. Ji, and Y. H. Lee, “Association between tumor necrosis factor-α promoter -308 A/G, -238 A/G, interleukin-6 -174 G/C and -572 G/C polymorphisms and periodontal disease: a meta-analysis,” Molecular Biology Reports, vol. 40, no. 8, pp. 5191–5203, 2013. View at Publisher · View at Google Scholar · View at Scopus
  23. X. Chen, J. Huang, L. Zhong, and C. Ding, “Quantitative assessment of the associations between interleukin-8 polymorphisms and periodontitis susceptibility,” Journal of Periodontology, vol. 86, no. 2, pp. 292–300, 2015. View at Publisher · View at Google Scholar · View at Scopus
  24. Q. Zhong, C. Ding, M. Wang, Y. Sun, and Y. Xu, “Interleukin-10 gene polymorphisms and chronic/aggressive periodontitis susceptibility: a meta-analysis based on 14 case-control studies,” Cytokine, vol. 60, no. 1, pp. 47–54, 2012. View at Publisher · View at Google Scholar · View at Scopus
  25. Z.-G. Li, J.-J. Li, C.-A. Sun, Y. Jin, and W.-W. Wu, “Interleukin-18 promoter polymorphisms and plasma levels are associated with increased risk of periodontitis: a meta-analysis,” Inflammation Research, vol. 63, no. 1, pp. 45–52, 2014. View at Publisher · View at Google Scholar · View at Scopus
  26. D. Moher, A. Liberati, J. Tetzlaff, and D. G. Altman, “Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement,” PLoS Medicine, vol. 6, no. 7, p. e1000097, 2009. View at Publisher · View at Google Scholar
  27. T. C. Lins, R. G. Vieira, B. S. Abreu, D. Grattapaglia, and R. W. Pereira, “Genetic composition of Brazilian population samples based on a set of twenty eight ancestry informative SNPs,” American Journal of Human Biology, vol. 22, no. 2, pp. 187–192, 2010. View at Publisher · View at Google Scholar · View at Scopus
  28. M. Smith, G. J. Seymour, and M. P. Cullinan, “Histopathological features of chronic and aggressive periodontitis,” Periodontology 2000, vol. 53, no. 1, pp. 45–54, 2010. View at Publisher · View at Google Scholar · View at Scopus
  29. G. C. Armitage, “Comparison of the microbiological features of chronic and aggressive periodontitis,” Periodontology 2000, vol. 53, no. 1, pp. 70–88, 2010. View at Publisher · View at Google Scholar · View at Scopus
  30. M. I. Ryder, “Comparison of neutrophil functions in aggressive and chronic periodontitis,” Periodontology 2000, vol. 53, no. 1, pp. 124–137, 2010. View at Publisher · View at Google Scholar · View at Scopus
  31. M. Kebschull, P. Guarnieri, R. T. Demmer, A. L. Boulesteix, P. Pavlidis, and P. N. Papapanou, “Molecular differences between chronic and aggressive periodontitis,” Journal of Dental Research, vol. 92, no. 12, pp. 1081–1088, 2013. View at Publisher · View at Google Scholar · View at Scopus
  32. J.-S. Deng, P. Qin, X.-X. Li, and Y.-H. Du, “Association between interleukin-1β C (3953/4)T polymorphism and chronic periodontitis: evidence from a meta-analysis,” Human Immunology, vol. 74, no. 3, pp. 371–378, 2013. View at Publisher · View at Google Scholar · View at Scopus
  33. J. R. Gonzales, J. Michel, A. Diete, J. M. Herrmann, R. H. Bödeker, and J. Meyle, “Analysis of genetic polymorphisms at the interleukin-10 loci in aggressive and chronic periodontitis,” Journal of Clinical Periodontology, vol. 29, no. 9, pp. 816–822, 2002. View at Publisher · View at Google Scholar · View at Scopus
  34. L. Scapoli, A. Girardi, A. Palmieri et al., “IL6 and IL10 are genetic susceptibility factors of periodontal disease,” Dental Research Journal, vol. 9, no. 2, pp. 197–201, 2012. View at Google Scholar
  35. L. Chai, Y.-Q. Song, and W. K. Leung, “Genetic polymorphism studies in periodontitis and Fcγ receptors,” Journal of Periodontal Research, vol. 47, no. 3, pp. 273–285, 2012. View at Publisher · View at Google Scholar · View at Scopus
  36. G. Prakash, M. Umar, S. Ajay et al., “COX-2 gene polymorphisms and risk of chronic periodontitis: a case-control study and meta-analysis,” Oral Diseases, vol. 21, no. 1, pp. 38–45, 2015. View at Publisher · View at Google Scholar · View at Scopus
  37. A. S. Schaefer, G. M. Richter, M. Nothnagel et al., “COX-2 is associated with periodontitis in europeans,” Journal of Dental Research, vol. 89, no. 4, pp. 384–388, 2010. View at Publisher · View at Google Scholar · View at Scopus
  38. A. Daing, S. V. Singh, C. S. Saimbi, M. A. Khan, and S. K. Rath, “Cyclooxygenase 2 gene polymorphisms and chronic periodontitis in a North Indian population: a pilot study,” Journal of Periodontal and Implant Science, vol. 42, no. 5, pp. 151–157, 2012. View at Publisher · View at Google Scholar · View at Scopus
  39. G. Li, Y. Yue, Y. Tian et al., “Association of matrix metalloproteinase (MMP)-1, 3, 9, interleukin (IL)-2, 8 and cyclooxygenase (COX)-2 gene polymorphisms with chronic periodontitis in a Chinese population,” Cytokine, vol. 60, no. 2, pp. 552–560, 2012. View at Publisher · View at Google Scholar · View at Scopus
  40. N. Silva, N. Dutzan, M. Hernandez et al., “Characterization of progressive periodontal lesions in chronic periodontitis patients: levels of chemokines, cytokines, matrix metalloproteinase-13, periodontal pathogens and inflammatory cells,” Journal of Clinical Periodontology, vol. 35, no. 3, pp. 206–214, 2008. View at Publisher · View at Google Scholar · View at Scopus