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International Journal of Dentistry
Volume 2017 (2017), Article ID 2857629, 4 pages
https://doi.org/10.1155/2017/2857629
Research Article

Correlation of Salivary Statherin and Calcium Levels with Dental Calculus Formation: A Preliminary Study

1Oral Pathology and Oral Medicine, Faculty of Dentistry, MAHSA University, Bandar Saujana Putra, 41200 Jenjarom, Selangor, Malaysia
2Department of Dental Public Health, Faculty of Dentistry, MAHSA University, Bandar Saujana Putra, 41200 Jenjarom, Selangor, Malaysia
3Oral Diagnostic and Surgical Science Division, International Medical University, No. 126, Jalan 19/155B, 57000 Bukit Jalil, Kuala Lumpur, Malaysia
4Department of Pedodontics, Faculty of Dentistry, MAHSA University, Bandar Saujana Putra, 41200 Jenjarom, Selangor, Malaysia
5Biomedical Sciences, MAHSA University, Bandar Saujana Putra, 41200 Jenjarom, Selangor, Malaysia

Correspondence should be addressed to Deepak Gowda Sadashivappa Pateel

Received 20 December 2016; Accepted 23 April 2017; Published 10 May 2017

Academic Editor: Shinn-Jyh Ding

Copyright © 2017 Deepak Gowda Sadashivappa Pateel et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Background. Salivary constituents have a wide range of functions including oral calcium homeostasis. Salivary proteins such as statherin inhibit crystal growth of calcium phosphate in supersaturated solutions and interact with several oral bacteria to adsorb on hydroxyapatite. Concurrently, saliva, which is supersaturated with respect to calcium phosphates, is the driving force for plaque mineralization and formation of calculus. Thus, the aim of the present study was to estimate and correlate salivary statherin and calcium concentration to the dental calculus formation. Methods. A cross-sectional study was conducted to assess the relationship between salivary statherin, calcium, and dental calculus among 70 subjects, aged 20–55 years. Subjects were divided into 3 groups based on the calculus scores as interpreted by Calculus Index which was followed by collection of whole saliva using Super•SAL™. Salivary calcium levels were assessed by calorimetric method using Calcium Assay kit (Cayman Chemical, Michigan, USA) and statherin levels by using ELISA Kit (Cusabio Biotech). Results. Statherin levels showed a weak negative correlation with the calcium levels and with calculus formation. The mean salivary statherin and calcium concentration were found to be 0.96 μg/ml and 3.87 mg/ml, respectively. Salivary statherin levels differed significantly among the three groups (). Conclusions. Our preliminary data indicates that statherin could possibly play a role in the formation of dental calculus.