Figure 3: (a) Solubilisation of calcium from HA beads following incubation of S. mutans with manuka and clover honeys at 37°C and 4°C. Significantly different from water control (; one-way ANOVA with Dunnett’s post hoc test). (b) Relationship between solubilised calcium and final proton concentration. Correlation between calcium solubilisation and [H+] ( = 0.770, ) Spearman’s rho test. MH25+: manuka honey NPA25+; MH20+: manuka honey NPA 20+; CH: clover honey.