Zinc, Copper, and Iron in Oral Submucous Fibrosis: A Meta-Analysis

Table 2

Zn/Cu ratios calculated from different studies.

Reference	Biomarker	Controls	OSMF	Total sample	Difference in Zn/Cu (OSMF-control)
Gupta et al. [12]	Serum	0.87	0.72	50	−0.15
Varghese et al. [50]	Serum	0.92	0.85	100	−0.07
Nayak et al. [65]	Serum	0.88	0.92	40	0.04
Balpande and Sathawane [23]	Serum	1.72	1.09	60	−0.63
Ayinamudi and Narsimhan [63]	Serum	0.05	0.04	21	−0.01
Shettar [31]	Serum	0.96	0.76	60	−0.2
Neethi et al. [55]	Serum	0.73	0.7	60	−0.03
Khanna et al. [34]	Serum	1.47	1.32	60	−0.15
Kode and Karjodkar [28]	Serum	1.48	2.05	45	0.57
Kode and Karjodkar [28]	Saliva	13.23	14.7	45	1.47
Hosthor et al. [29]	Serum	0.77	0.19	60	−0.58
Shetty et al. [30]	Saliva	0.78	0.28	100	−0.5
Yadav et al. [35]	Saliva	1.19	0.47	100	−0.72
More and Patel [26]	Serum	2.92	0.86	60	−2.06