Zinc, Copper, and Iron in Oral Submucous Fibrosis: A Meta-Analysis

Table 3

Cu/Fe ratios calculated from studies included.

Reference	Biomarker	Controls	OSMF	Total sample	Difference in Zn/Cu (OSMF-control)
Anuradha and Devi [27]	Plasma	1.2	2	44	0.8
Luqumun et al. [51]	Serum	1.06	1.37	30	0.31
Khanna and Karjodkar [52]	Serum	1.11	1.26	60	0.15
Balpande and Sathawane [23]	Serum	1.22	2.09	60	0.87
Tadakmadla et al. [33]	Serum	0.88	1.16	100	0.28
Kode and Karjodkar [28]	Serum	0.99	1.36	45	0.37
Kode and Karjodkar [28]	Saliva	0.11	0.33	45	0.22
Hosthor et al. [29]	Serum	1.06	5.25	60	4.19
Shetty et al. [30]	Saliva	0.61	2.45	100	1.84
Okade et al. [36]	Saliva	0.1	1.75	60	1.65
Tiwari et al. [38]	Serum	0.99	1.25	70	0.26
Kumar et al. [64]	Serum	0.89	1.15	70	0.26