Research Article
Variation of Energy in Photobiomodulation for the Control of Radiotherapy-Induced Oral Mucositis: A Clinical Study in Head and Neck Cancer Patients
Table 1
Protocols of laser irradiation (adapted from Zecha et al. [
11]).
| | Protocol | Group 0.25 J | Group 1.0 J |
| Source (laser device) | Indium gallium arsenide phosphide semiconductor laser | Indium gallium arsenide phosphide semiconductor laser | Wavelength | 660 nm (visible red) | 660 nm (visible red) | Power | 25 mW | 100 mW | Beam area | 4 mm2 | 3 mm2 | Energy (radiation) | 0.25 J | 1.0 J | Time | 10 s | 10 s | Dosage (fluence or energy density) | 6.3 J/cm2 | 33 J/cm2 | Operating mode | Continuous wave | Continuous wave | Physical relationship to the organ | Intraoral, direct contact with oral mucosa | Intraoral, direct contact with oral mucosa | Schedule | Concomitant to radiotherapy | Concomitant to radiotherapy |
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Twin Flex Evolution, MM Optics Ltda, São Carlos, São Paulo, Brazil; Laser Duo, MM Optics Ltda, São Carlos, São Paulo, Brazil. |