β₂-Microglobulin and Neutrophil Gelatinase-Associated Lipocalin, Potential Novel Urine Biomarkers in Periodontitis: A Cross-Sectional Study in Japanese

Table 4

Multivariate regression analysis of the associations between β₂-MG and variables.

	Standardized β	t	P value
Age (years)	0.174	1.783	0.078
Smoking status (pack-years)	0.021	0.200	0.842
BMI	−0.174	−1.605	0.112
eGFR (ml/min/1.73 m^2)	0.049	0.462	0.645
HbA1C (%)	0.040	0.392	0.696
Hs-CRP	−0.032	−0.317	0.752
BOP (%)	−0.060	−0.470	0.639
Total bacteria in the subgingival plaque (copy)	−0.098	−0.851	0.397
PD ≥ 6 mm (number of sites)	0.280	2.234	0.028

Multivariate regression analysis was performed by the force entry model. Age, smoking status, BMI, eGFR, HbA1C, hs-CRP, BOP, total bacteria in the subgingival plaque, and the number of sites with PD ≥ 6 mm were used as variables. To obtain the normal distribution, the values of total bacteria in the subgingival plaque were used after logarithmic conversion. hs-CRP and the number of sites with PD ≥ 6 mm were converted to an ordinal value as described in Materials and Methods. R = 0.355; adjusted R². Statistically significant values are indicated by .