Interleukin-1 Gene Variability and Plasma Levels in Czech Patients with Chronic Periodontitis and Diabetes Mellitus

Table 5

Differences in IL-1β levels between unstimulated and stimulated PBMCs ().

PBMCs	IL-1β levels (pg/mL), median (IQR)	value
Stimulated by
PWM	481.97 (100.89–938.66)	<0.001
PWM + ConA	533.30 (141.45–950.37)	<0.001
HSP70	95.28 (23.36–371.60)	0.02
A. actinomycetemcomitans	483.93 (162.48–890.50)	<0.001
P. gingivalis	27.88 (6.47–118.14)	0.34
P. intermedia	249.38 (57.83–441.80)	<0.001
T. forsythia	201.08 (44.39–583.32)	<0.001
Unstimulated	52.55 (14.90–153.54)	—

CI = confidence interval; ConA = Concavalin A; HSP 70 = heat shock protein 70; OR = odds ratio; PBMCs = peripheral blood mononuclear cells; PWM = Pokeweed mitogen. The Wilcoxon matched pair test was used to calculate the significant difference.