Development and Formulation of the Experimental Dentifrice Based on Passiflora mollissima (Tumbo) with and without Fluoride Anion: Antibacterial Activity on Seven Antimicrobial Strains : Table 4

Table 4: Comparison of the antimicrobial activity of tumbo dentifrice against different commercial toothpastes.


Microorganisms	Groups	Mean ± SD	Min	Max

S. mutans	Pulp	20.0 ± 2.1	17.8	25.2	0.093	0.651⁺⁺
	Peel	16.0 ± 1.5	14.6	18.6	0.008
	Dento Herbal®	17.0 ± 0.6	16.2	17.8	0.734
	Colgate Herbal®	16.9 ± 0.8	16.1	17.8	0.386
	Kolynos Herbal®	15.1 ± 0.2	14.9	15.5	0.392
	Sensodyne®	11.2 ± 0.8	10.0	12.0	0.191
	Parodontax®	30.2 ± 1.5	28.9	32.5	0.194

E. faecalis	Pulp	15.5 ± 1.1	13.8	17.3	0.492	0.906⁺
	Peel	15.5 ± 0.4	15.0	16.5	0.647
	Dento Herbal®	12.8 ± 0.4	12.3	13.2	0.303
	Colgate Herbal®	13.9 ± 0.8	12.9	14.9	0.900
	Kolynos Herbal®	14.2 ± 0.6	13.5	14.9	0.513
	Sensodyne®	10.6 ± 0.3	10.2	11.0	0.408
	Parodontax®	15.7 ± 0.2	15.5	16.1	0.649

Actinomyces	Pulp	18.3 ± 1	17.3	20.2	0.012	0.143⁺⁺
	Peel	18.7 ± 3.3	16.3	29.1	0.000
	Dento Herbal®	14.1 ± 0.4	13.8	14.7	0.303
	Colgate Herbal®	15 ± 0.1	14.8	15.2	0.714
	Kolynos Herbal®	13.4 ± 0.1	13.2	13.6	0.000
	Sensodyne®	13.2 ± 0.2	12.9	13.5	0.000
	Parodontax®	14.1 ± 0.5	13.5	14.9	0.889

Lactobacillus	Pulp	20.8 ± 0.6	19.8	22.1	0.623
	Peel	17.6 ± 0.2	17.2	18.1	0.842
	Dento Herbal®	17.7 ± 0.6	17.0	18.3	0.443
	Colgate Herbal®	21.2 ± 0.9	20.1	22.3	0.997
	Kolynos Herbal®	22.1 ± 0.8	20.9	23.0	0.696
	Sensodyne®	15.5 ± 2.8	12.9	18.3	0.126
	Parodontax®	15.2 ± 0.2	14.9	15.5	0.910

C. albicans	Pulp	17.4 ± 1.4	15.7	19.7	0.730
	Peel	21.1 ± 0.9	20.2	22.6	0.534
	Dento Herbal®	17.9 ± 0.6	17.3	18.7	0.513
	Colgate Herbal®	21.7 ± 0.4	21.2	22.3	0.970
	Kolynos Herbal®	20.9 ± 1.5	19.9	23.2	0.025
	Sensodyne®	0	0	0	—
	Parodontax®	24.4 ± 0.6	23.8	25.0	0.111

S. sanguinis	Pulp	14.9 ± 0.1	14.7	15.3	0.331	1.000⁺
	Peel	15.9 ± 0.4	15.3	16.6	0.447
	Dento Herbal®	19.7 ± 0.5	19.0	20.2	0.369
	Colgate Herbal®	21.1 ± 0.5	20.4	21.8	0.994
	Kolynos Herbal®	20.4 ± 1.1	19.6	22.1	0.211
	Sensodyne®	0	0	0	—
	Parodontax®	26.1 ± 0.5	25.6	26.9	0.680

S. oralis	Pulp	14.5 ± 0.9	13.6	16.4	0.016	0.425⁺⁺
	Peel	16.5 ± 0.4	15.6	17.3	0.699
	Dento Herbal®	16 ± 0.6	15.2	16.8	0.999
	Colgate Herbal®	15.6 ± 0.5	15.1	16.3	0.688
	Kolynos Herbal®	19.9 ± 0.1	19.8	20.2	0.849
	Sensodyne®	0	0	0	—
	Parodontax®	17.7 ± 0.4	17.2	18.2	0.420

All measurements were made in mm. The concentrations were calculated from the dilutions of the active ingredient; the Sensodyne control group was excluded from any statistical analysis because the antimicrobial activity was not present. Shapiro–Wilk test. ⁺Student t-test. ⁺⁺Mann–Whitney U test. ANOVA test. ^†Kruskal–Wallis test. Level of significance .