Research Article
HIF-1α Is Associated with Resistance to Hypoxia-Induced Apoptosis in Ameloblastoma
Table 1
The
values of HIF-1
α, p53, BNIP3, Bcl-2, IAP-2, GLUT1, and Bax with expression in AMB and DF, Student’s
t, and Mann–Whitney tests.
| Protein | AME (n = 20) | DF (n = 10) | value | Mean | SD | Mean | SD |
| HIF-1α | 59.04 | ±5.61 | 12.81 | ±1.68 | <0.0001 | p53 | 46.26 | ±4.24 | 12.68 | ±2.61 | <0.0001 | BNIP3 | 53.31 | ±6.11 | 10.22 | ±1.57 | <0.0001 | Bcl-2 | 59.03 | ±5.64 | 11.87 | ±3.14 | <0.0001 | IAP-2 | 52.21 | ±6.02 | 11.94 | ±1.72 | <0.0001 | GLUT1 | 51.65 | ±11.19 | 11.71 | ±1.40 | <0.0001 | Bax | 45.94 | ±5.05 | 9.81 | ±1.67 | <0.0001 |
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AMB: ameloblastoma; DF: dental follicle.
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