Research Article

The Impact of DNA Methylation on IL6 mRNA Levels in Hematinic Deficiency and Atopy-Associated Recurrent Aphthous Stomatitis Patients

Table 1

Characteristics of subjects.

CharacteristicsGroup value
RAS (n = 23)Control (n = 21)

Gender#0.305
 Male10 (43.5%)6 (28.6%)
 Female13 (56.5%)15 (71.4%)

Age (year)23.5 (4.2)22.7 (3.8)0.405

Hematinic deficiency
 Vitamin B-12 (pg/mL)1435.2 (464.6–4387.4)2150 (852.2–3086)0.001
 Ferritin (ng/mL)52.7 (3.02–174.97)45.26 (2.53–140.13)0.597
 Folic acid (ng/mL)19.4 (8.08–40.64)20.45 (6.03–46.84)0.264

Atopy0.001
 Dermatitis atopic (DA)80
 DA and bronchial asthma20
 Nonatopic1321

Total IgE (IU/mL)155.7 (2.3–234.8)167.32 (73.7–363.8)0.540

Chi-square test. Mann–Whitney Test. Average (standard deviation). Median (range).