Periodontal Treatment Improves Serum Levels of Leptin, Adiponectin, and C-Reactive Protein in Thai Patients with Overweight or Obesity
Table 3
Levels of cytokines at baseline, as well as at 3 and 6 months after periodontal treatment, according to BMI and periodontal disease status.
Owt/Ob
Nwt
With SP
Without SP
With SP
Without SP
Leptin (ng/mL)
Baseline
16.17 (8.32, 28.93)
15.76 (11.40, 23.35)
12.13 (9.93, 20.70)
6.69 (5.99, 11.29)
3 months
10.33 (6.55, 24.21)
12.63 (7.06, 18.02)
9.04 (5.92, 16.06)
6.70 (4.91, 10.83)
6 months
12.80 (7.18, 21.81)
13.61 (9.90, 20.42)
10.10 (6.16, 17.25)
6.70 (4.72, 7.75)
†
0.009
<0.001
0.015
0.156
Adiponectin (μg/mL)
Baseline
4.57 (2.90, 6.45)
3.29 (2.00, 4.82)
4.23 (2.69, 6.44)
3.22 (2.70, 5.02)
3 months
6.09 (5.24, 7.71)
4.36 (3.31, 6.22)
6.04 (3.12, 7.19)
5.54 (3.31, 8.34)
6 months
6.81 (5.35, 7.96)
4.18 (3.25, 7.68)
5.85 (3.65, 9.08)
5.48 (4.86, 7.92)
0.009
<0.001
0.015
0.004
CRP (μg/mL)
Baseline
3.17 (2.08, 8.04)
3.35 (1.41, 5.64)
1.58 (0.66, 3.97)
0.58 (0.41, 4.36)
3 months
1.88 (0.93, 4.68)
2.59 (1.26, 2.96)
0.98 (0.37, 2.69)
0.43 (0.15, 4.25)
6 months
2.10 (0.72, 5.29)
2.47 (0.88, 3.26)
0.84 (0.44, 2.71)
0.50 (0.20, 6.33)
0.011
<0.001
0.022
0.018
Data are shown as median (Q1, Q3). †, Friedman test; CRP, C-reactive protein; Owt, overweight; Ob, obesity; Nwt, normal weight; SP, severe periodontitis.
