Antibiotic Therapy in Dentistry

Table 4

FDA risk classes of antibiotics used during pregnancy.

Category risk factor	Antibiotics	Side effects
A
Satisfactory well-controlled studies on humans showing no hazard to the fetus
B	Amoxicillin
Animal studies demonstrate no risk, but no human studies have been performed or human studies have demonstrated no risk	Cephalexin
	Chlorhexidine
	Clindamycin
	Erythromycin
	Metronidazole
	Penicillin
	Azithromycin
C	Ciprofloxacin	Chondrotoxic in growing rats
Studies on animals establishing fetal hazards and no exact studies on human being	Moxifloxacin	Chondrotoxic in growing rats
	Clarithromycin	Increased risk of miscarriage
D	Doxycycline	Intrinsic dental staining
Evidence of risk to the fetus can be used in exceptional cases or circumstances	Tetracycline	Intrinsic dental staining
X
The hazards of using the drug in pregnant women far more than the benefits