Vitamin D Supplementation for Prevention of Dental Implant Failure: A Systematic Review

Table 2

Data from case reports, case series, and retrospective studies.

Author	Title	Study type	Results
Mango et al., 2018	Low serum level vitamin D and early dental implant failure	Retrospective study	No significant relationship between low vitamin D levels and an increase in the risk of EDIF
Wagner et al., 2017	Does osteoporosis influence the marginal peri-implant bone level in female patients? A cross-sectional study in a matched collective	Retrospective parallel-group	A significant and positive effect of vitamin D on marginal bone loss at the M and D aspect of the dental implants
Mangano et al., 2016	Is low serum vitamin D associated with early dental implant failure? A retrospective evaluation of 1625 implants placed in 822 patients	Retrospective study	Increase in EDIF with compromised levels of vitamin D, but statistically not significant
Fretwurst et al., 2017	Vitamin D deficiency in early implant failure: Two case reports	Case series	The implant was successful after administration of vitamin D
Bryce and macbeth, 2014	Vitamin D deficiency as a suspected causative factor in the failure of an immediately placed dental implant: A case report	Case report	The EDIFs occurred after immediate implant placement due to severe vitamin D deficiency