Equisetum arvense Inhibits Alveolar Bone Destruction in a Rat Model with Lipopolysaccharide (LPS)-Induced Periodontitis

Figure 2

Immunohistochemical examination of periodontal tissue. (a) Hematoxylin and eosin (H&E) staining of tissue obtained from animals 3 days after Escherichia coli (E. coli)-lipopolysaccharide (LPS) topical administration. (A) Control (PS-applied control), (B) E. coli-LPS, (C) E. coli-LPS/Equisetum arvense extract (EA) application. Immunoexpression of the receptor activator of NF-κB ligand (RANKL) in the upper part of the alveolar bone area, (D, D′) control, (E, E′) E. coli-LPS, and (F, F′) E. coli-LPS/EA application. Scale bars = 100 μm. (b) H&E staining of tissue obtained from animals 3 days after E. coli-LPS topical administration. (A) Control, (B) E. coli-LPS, and (C) E. coli-LPS/EA application. Immunoexpression of osteoprotegerin (OPG) in the upper part of the alveolar bone area, (D, D′) control, (E, E′) E. coli-LPS, and (F, F′) E. coli-LPS/EA application. Scale bars = 100 μm.

(a)

(b)