Research Article

Nitrogen-Containing Bisphosphonates Downregulate Cathepsin K and Upregulate Annexin V in Osteoclasts Cultured In Vitro

Figure 5

Comparison of Annexin V expression in cultured osteoclasts stimulated in vitro with alendronate (95.4 mM) or risedronate (95.4 mM) with that in control cells. Significant upregulation of Annexin V at 0 and 48 h with alendronate and at 0 and 48 h with risedronate; and .