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International Journal of Endocrinology
Volume 2010 (2010), Article ID 521457, 6 pages
Research Article

Vitamin D Deficiency—A Clinical Spectrum: Is There a Symptomatic Nonosteomalacic State?

1Health Promotion & Education, University of Cincinnati, P. O. Box 210068, Cincinnati, OH 45221-0068, USA
2Division of Rheumatology, P.D. Hinduja Hospital and Medical Research Centre, Veer Savarkar Marg, Mahim, Mumbai 400016, India

Received 21 March 2009; Accepted 3 August 2009

Academic Editor: Suzanne E. Judd

Copyright © 2010 Amar Kanekar et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Vitamin D deficiency is not uncommon even in the sunny land of India. Lack of sun exposure and inadequate oral intake are both responsible for vitamin D deficiency. This article provides a retrospective, examining the effects of Vitamin D deficiency in 71 patients. The study's inclusion criterion was low vitamin D level combined with musculoskeletal symptoms but without the presence of osteomalacia. All patients in this study were suspected to have vitamin D deficiency. The data were retrieved from the case-charts of patients seen between 1996 and 2001 at the rheumatology services of Hinduja Hospital, Mumbai, India. This study found no correlation between Vitamin D levels and symptoms, or between the severity of Vitamin D deficiency and the number of symptoms displayed. Subclinical vitamin D deficiency or preosteomalacic state was the term coined for individuals with vitamin D deficiency producing nonspecific musculoskeletal symptoms in the absence of clinical osteomalacia.