Graves' Disease Associated with Cerebrovascular Disease and Antiphospholipid Antibody Syndrome

Table 2

Clinical and laboratory criteria of antiphospholipid antibody syndrome [6].

Clinical criteria	(1) Vascular thrombosis: one or more clinical episodes of arterial, venous, or small vessel thrombosis, in any tissue or organ
	(2) Pregnancy morbidity: one or more unexplained deaths of beyond the 10th week of gestation, one or more premature births of a morphologically normal neonate before the 34th week of gestation, or three or more unexplained consecutive spontaneous abortions before the 10th week of gestation
Laboratory criteria	(1) Lupus anticoagulant present in plasma, on two or more occasions at least 12 weeks apart
	(2) Anticardiolipin antibody of IgG and/or in high titer >40 GPL or MPL
	(3) Anti-β2-glycoprotein-I antibody of IgG and/or IgM isotype present on two or more occasions