Review Article

Impact of Sleep and Its Disturbances on Hypothalamo-Pituitary-Adrenal Axis Activity

Figure 3

Effect of an 8-hour sleep delay on cortisol profiles. Mean 24-hour (+ SEM) cortisol profiles under baseline conditions (bedtimes from 23:00 to 7:00), and one, three, five days after an 8-hour delay of the sleep-wake and dark-light cycles (bedtimes from 7:00 to 15:00). Black bars represent the sleep periods. (Adapted from Buxton et al. [67].)
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