Research Article

Chronic Sleep Disturbance Impairs Glucose Homeostasis in Rats

Figure 3

Blood glucose and plasma insulin levels in response to a 30-minutes intravenous glucose infusion after 8 days of sleep restriction (graphs (c) and (f), ), sleep disturbance (graphs (b) and (e), ), or control (graphs (a) and (d), ). Each graph presents the glucose or insulin profiles under pre-experimental baseline conditions (Baseline: open circles) and after 8 days of sleep disturbance (Experiment: closed circles). The horizontal grey bars at the bottom of each graph represent the 30 minutes of 15% glucose infusion. Data are average values ± SEM. Asterisks indicate a significant difference between baseline and experimental conditions ( P < .05).
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(a)
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(b)
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(c)
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(d)
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(e)
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(f)