The Role of −786T/C Polymorphism in the Endothelial Nitric Oxide Synthase Gene in Males with Clinical and Biochemical Features of the Metabolic Syndrome

Table 1

Baseline characteristics of study group and control group.

Parameter	Study group	Control group	𝑃-value*
Age	46,35 ± 6,64	43,22 ± 5,84	0,001
BMI (kg/m^2)	30,49 ± 2,91	24,46 ± 2,08	<0,001
Fatty tissue percentage (%)	28,81 ± 5,72	18,53 ± 4,37	<0,001
Waist circumference (cm)	102,09 ± 7,81	86,79 ± 4,80	<0,001
Hip circumference (cm)	106,75 ± 5,75	98,8 ± 3,51	<0,001
WHR	0,96 ± 0,04	0,88 ± 0,03	<0,001
CHOLT (mmol/L)	5,64 ± 0,93	5,01 ± 0,79	<0,001
LDL (mmol/L)	3,44 ± 0,89	2,84 ± 0,72	<0,001
HDL (mmol/L)	1,31 ± 0,29	1,64 ± 0,42	<0,001
TG (mmol/L)	2,30 ± 1,32	1,18 ± 0,45	<0,001
Uric acid (μmol/L)	368,08 ± 67,13	306,48 ± 61,91	<0,001
CRP (mg/L)	2,89 ± 2,96	1,08 ± 0,92	<0,001
Leptine (ng/mL)	9,59 ± 5,59	4,61 ± 2,04	<0,001
Adiponectine (μg/mL)	6,95 ± 3,50	8,94 ± 3,16	0,002
Left IMT (cm)	0,59 ± 0,15	0,51 ± 0,09	<0,001
Right IMT (cm)	0,59 ± 0,17	0,50 ± 0,08	<0,001
HOMA-IR	3,45 ± 2,21	1,37 ± 0,69	<0,001
QUICKI	0,68 ± 0,41	0,78 ± 0,50	0,18

Results expressed as mean values ± SD. Abbreviations: BMI: body mass index, WHR: waist-to-hip ratio, CHOLT: total cholesterol level, LDL: low density lipoproteins, HDL: high density lipoproteins, TG: trigllcerides, CRP: C-reactive protein, IMT: intima-media thickness of carotid arteries, HOMA-IR: Homeostasis Model of Assessment-Insulin Resistance, QUICKI: Quantitative Insulin-Sensitivity Check Index.
* 𝑃-value refers to the Mann-Whitney 𝑈 test.