Association between Serum Uric Acid Levels and Diabetes Mellitus

Table 2

Association between serum uric acid level and diabetes mellitus.

Serum uric acid level*	Number at risk (Diabetes cases)	Age- and sex-adjusted odds ratio (95% confidence interval)	Multivariable-adjusted odds ratio; (95% confidence interval)^†
Quartile 1 (<4.30 mg/dL)	3482 (305)	1 (referent)	1 (referent)
Quartile 2 (4.30–5.20 mg/dL)	3624 (206)	0.63 (0.44–0.91)	0.54 (0.36–0.80)
Quartile 3 (5.30–6.20 mg/dL)	3499 (185)	0.62 (0.45–0.85)	0.40 (0.29–0.56)
Quartile 4 (>6.20 mg/dL)	3539 (325)	0.54 (0.30–097)	0.48 (0.35–0.66)
P trend		0.0023	<0.0001

*Serum uric acid quartiles: <4.3 mg/dL, 4.30–5.20 mg/dL, 5.30–6.20 mg/dL, >6.20 mg/dL.
^†Adjusted for age (years), sex (men, women), race-ethnicity (non-Hispanic whites, non-Hispanic blacks, Mexican Americans, etc.), education categories (<high school, high school, >high school), smoking (never, former, current), alcohol intake (never, former, current), BMI (normal, overweight, obese), hypertension (absent, present), and serum total cholesterol (mg/dL).