Association between Serum Uric Acid Levels and Diabetes Mellitus

Table 3

Association between serum uric acid level and diabetes mellitus by gender.

Serum uric acid level*	Number at risk (Diabetes cases)	Multivariable-adjusted odds ratio (95% confidence interval)^†
Women
Quartile 1 (<3.8 mg/dL)	1839 (113)	1 (referent)
Quartile 2 (3.8–4.5 mg/dL)	2046 (121)	0.79 (0.49–1.28)
Quartile 3 (4.6–5.4 mg/dL)	1843 (103)	0.53 (0.33–0.83)
Quartile 4 (>5.4 mg/dL)	1881 (209)	0.78 (0.51–1.20)
P trend		0.3590
Men
Quartile 1 (<5.20 mg/dL)	1643 (192)	1 (referent)
Quartile 2 (5.20–5.9 mg/dL)	1578 (85)	0.42 (0.23–0.76)
Quartile 3 (6.0–6.8 mg/dL)	1656 (82)	0.35 (0.21–0.58)
Quartile 4 (>6.8 mg/dL)	1658 (116)	0.32 (0.20–0.51)
P trend		<0.0001

*Serum uric acid quartiles: <4.3 mg/dL, 4.30–5.20 mg/dL, 5.30–6.20 mg/dL, >6.20 mg/dL.
^†Adjusted for age (years), race-ethnicity (non-Hispanic whites, non-Hispanic blacks, Mexican Americans, etc.), education categories (<high school, high school, >high school), smoking (never, former, current), alcohol intake (never, former, current), BMI (normal, overweight, obese), hypertension (absent, present), and serum total cholesterol (mg/dL).