Procoagulant and Anticoagulant Factors in Childhood Hypothyroidism

Table 4

Coagulation test results of the patients before and after treatment.

Variables	Before	After	𝑃
PT (sc)	11.7 (1.60)	11.6 (1.20)	0.264^*
aPTT (sc)	35.1 ± 5.48	31.6 ± 2.68	0.006^†
INR (ratio)	1.1 (0.15)	1.1 (0.11)	0.264^*
Fibrinogen (mg/dL)	274.9 ± 68.36	303.6 ± 50.50	0.03^†
TT (sc)	19.5 (3.25)	15.6 (1.40)	0.007^*
FII (%)	102.7 (25.15)	111.4 (19.60)	0.245^*
FV (%)	105.6 (31.90)	118.2 (24.30)	0.054^*
FVII (%)	82.2 ± 20.63	80.3 ± 18.16	0.630^†
FVIII (%)	87.0 (43.70)	106.5 (32.50)	0.031^*
FIX (%)	104.4 (27.95)	109.6 (34.20)	0.068^*
FX (%)	99.5 ± 24.89	107.7 ± 20.43	0.110^†
FXII (%)	128.3 ± 29.20	126.4 ± 23.22	0.750^†
FXIII (%)	132.8 ± 25.40	140.2 ± 38.58	0.331^†
AP (%)	121.5 (28.00)	112.0 (10.50)	0.026^*
vWF (%)	92.4 (63.60)	106.4 (41.10)	0.025^*
AT (%)	92.0 (30.00)	107.0 (18.50)	0.028^*
PC (%)	83.0 (40.00)	92.0 (24.00)	0.036^*
PS (%)	71.5 ± 21.33	87.7 ± 15.78	<0.001^†
fPS (%)	80.4 ± 17.94	92.7 ± 19.58	0.003^†
PL (%)	93.0 (31.50)	90.0 (16.50)	0.439^*
APCR (ratio)	3.0 (0.35)	2.6 (0.55)	0.421^‡
LA (ratio)	1.1 (1.14)	1.2 (1.13)	0.41^‡

AP: antiplasmin; AT: antithrombin; F: factor; fPS: free protein S; PC: protein C; PL: plasminogen; PS: protein S; PT: prothrombin time; PTT: activated partial thromboplastin time; TT: thrombin time; vWF: vonWillebrand’s factor. ^*Mann Whitney U test, ^†Student’s t-test, ^‡Wilcoxon signed rank test.