The Effect of Puberty on Interaction between Vitamin D Status and Insulin Resistance in Obese Asian-Indian Children
Table 1
Descriptive characteristics of study population.
Parameter
Mean ± SD
Group A: serum 25(OH)D < 10 ng/mL
Group B: serum 25(OH)D ≥ 10 ng/mL
value
Number of subjects
62
41
21
Age (in yrs)
13.0 ± 3.1
12.6 ± 3.1
13.7 ± 3.1
0.2
BMI (Kg/M2)
29.3 ± 4.8
29.3 ± 5.2
29.3 ± 3.8
0.97
Waist circumference (cms)
89.6 ± 13.3
89.4 ± 15
90 ± 11.0
0.87
Hip circumference (cms)
97.8 ± 13.03
97.4 ± 13
99 ± 14
0.71
Waist hip ratio
0.92 ± 0.06
0.91 ± 0.06
0.91 ± 0.07
0.86
Systolic BP (mm of Hg)
120 ± 12
118 ± 12
124 ± 12
0.06
Diastolic BP (mm of Hg)
79 ± 8
78 ± 7
80 ± 9
0.55
Total cholesterol (mg/dL)
154 ± 30
155 ± 29
154 ± 34
0.94
Triglyceride (mg/dL)
116 ± 47
113 ± 49
122 ± 42
0.50
HDL cholesterol (mg/dL)
40 ± 6
40 ± 6
39 ± 4
0.78
LDL cholesterol (mg/dL)
92 ± 25
92 ± 24
91 ± 28
0.86
S.T4 (μg/dL)
9.44 ± 2.1
9.50 ± 2.2
9.31 ± 2.0
0.74
S.TSH (mIU/L)
3.79 ± 2.2
3.86 ± 2.4
3.65 ± 1.9
0.74
AST (IU/L)
34 ± 20
36 ± 24
30 ± 7
0.29
ALT (IU/L)
42 ± 40
46 ± 48
35 ± 14
0.32
Bl.glucose at 0 min (mg/dL)
95 ± 13
99 ± 17
93 ± 9
0.098
Bl.glucose at 60 min (mg/dL)
135 ± 33
141 ± 37
124 ± 22
0.06
Bl.glucose at 120 min (mg/dL)
120 ± 24
123 ± 26
114 ± 17
0.16
AUC glucose
241.7 ± 41.1
248.6 ± 45.7
231.3 ± 27.6
0.07
S.insulin at 0 min (mU/L)
20 ± 16
22 ± 18
15 ± 8
0.2
S.insulin at 60 min (mU/L)
120 ± 153
123 ± 118
118 ± 210
0.9
S.insulin at 120 min (mU/L)
120 ± 175
128 ± 162
105 ± 200
0.6
AUC insulin
185.8 ± 230.6
190.2 ± 185.1
177.1 ± 305.8
0.8
HOMA-IR
4.75 ± 3.7
5.17 ± 4.1
3.91 ± 2.5
0.2
WBISI
4.23 ± 4.0
4.05 ± 4.1
4.59 ± 3.7
0.39
HbA1c (%)
5.4 ± 0.4
5.4 ± 0.3
5.4 ± 0.5
0.93
Total body fat (%)
40.8 ± 6.6
42 ± 6.6
38.0 ± 5.7
0.015
Fat mass index (Kg/M2)
12.0 ± 3.1
12.7 ± 3.2
10.6 ± 2.3
0.007
Fat-free mass index (Kg/M2)
17.2 ± 2.9
17.0 ± 3.1
17.5 ± 2.4
0.53
Serum 25(OH)D (ng/mL)
8.5 ± 4.2
5.9 ± 1.4
13.6 ± 3.2
—
CIMT (mm)
0.06 ± 0.01
0.06 ± 0.01
0.05 ± 0.01
0.52
BMI: Body mass index, BP: blood pressure, AST: aspartate aminotransferase, ALT: alanine aminotreasferase, AUC: area under curve, WBISI: whole body insulin sensitivity index, CIMT: carotid intima media thickness.
