Research Article

A Cell Model for Conditional Profiling of Androgen-Receptor-Interacting Proteins

Table 2

Gene lists representing the biological processes (BP) “regulation of transcription” and “gene expression” identified by the bioinformatics tools “DAVID” and “g-profiler” as being overrepresented among the known AR-interacting proteins of the N-TAP-mAR purification. Listed are the interacting proteins, the AR is in bold face, that were unique for the proliferating cells (33), interacting proteins that were unique for the nonproliferating cells (37), and interacting proteins common to both (common).

Regulation of transcription (BP) DAVIDGene expression (BP) g-profiler
33Common3733Common37

KDM3AEP300EP300
SMARCA4SMARCA4
ARAR
WHSC1MED1WHSC1MED1
CTNNB1CTNNB1
MED17NR3C1MED17NR3C1
PRPF6PRPF6
KDM1AKDM1A
MED24SP1MED24SP1
TRP53TRP53
MYST2MYST2
DDX5SRCDDX5
DAXXDAXX
SMARCC1GATA3SMARCC1GATA3
RBM14SMARCD1RBM14
BRD7NPM1BRD7
GTF2F1CALCOCO1GTF2F1CALCOCO1
EHMT2EHMT2
FLNAFLNA
KDM5BKDM5B
NONONONO
NCOR2NCOR2
NCOA2NCOA2
PA2G4PA2G4
RB1RB1
STAT3STAT3
HDAC1HDAC1
SFPQSFPQ
TRIM24TRIM24
HDAC6PRKDC
COBRA1CALR
ATAD2XRCC6
MCM3SART3
BRD8
SMARCA2
KHDRBS1
ZFP318
TGFB1l
PSPC1
PIAS1