Arterial Hypertension, Metabolic Syndrome and Subclinical Cardiovascular Organ Damage in Patients with Asymptomatic Primary Hyperparathyroidism before and after Parathyroidectomy: Preliminary Results

Table 1

Demographic, biochemical, calcium-phosphorus mineral metabolism, and bone mineral density in studied groups.

	Age (yrs)	Sex (M/F)	BMI (kg/m²)	WC (cm)	SBP (mmHg)	DBP (mmHg)	HR (bpm)
PHPT (n.30)	54±12	8 M/22 F	27.4±4.4	95.7±11.8	144±10.2 *	90.4±10.3 *	75±6.4 *
EH (n.30)	55±5	9 M/21 F	27.1±2.3	90±3.5	135.3±5 *	84.4±5 *	71±8
NS (n.30)	55±6	9 M/21 F	26.1±2.19	85.7±2.19	129.3±4	78.4±4	69±9
𝑃	ns	ns	ns	ns	∗<0.001 versus NS	*<0.001 versus NS	*<0.001 versus EH-NS
	Creatinine (mg/dL)	Fasting blood glucose (mg/dL)	CT (mg/dL)	LDL-C (mg/dL)	HDL-C (mg/dL)	TG (mg/dL)	Uric acid (mg/dL)
PHPT (n.30)	0.96±0.4	92.6±7.5 *	227.4±26.2 *	146±21.3 *	54±6.2	135±21.7 *	6.9±2.6 *
EH (n.30)	1.02±0.03	102.5±14.5 *	217±41.3 *	133.7±36.4 *	55.3±13.9	140.7±33.5 *	5.07±2.1 *
NS (n.30)	0.94±0.3	83.9±4	192±17.5	116.8±18.5	57.4±7.4	94.5±16.1	3.6±1
𝑃	ns	*0.001 versus NS	*0.001 versus NS	*0.001 versus NS	ns	^∗0.001versus NS	^∗0.001 versus NS
	Calcium (mg/dL)	Ca^++ (mmol/L)	Phosphorous (mg/dL)	Mg^++ (mmol/L)	Ca Ur (mg/24 h)	PTH (pg/mL)	ALP (UI/L)
PHPT (n.30)	11.2±1.2 *	1.51±0.2 *	2.73±0.8 *	0.45±0.06 *	352±177 *	122±47.7 *	154±74.6 *
EH (n.30)	9.8±0.2	1.22±0.03	2.95±0.3	0.53±0.03	170±18.3	32±5.3	112±57
NS (n.30)	9.4±0.3	1.21±0.02	3.43±0.36	0.52±0.04	155±17.3	29±2.39	100±52
𝑃	*<0.001 versus EH-NS	*<0.001 versus EH-NS	*0.006 versus EH-NS	*0.006 versus EH-NS	*<0.001 versus EH-NS	*<0.001 versus EH-NS	*0.016 versus EH-NS
	BMD L1-L4 (gr/cm^2)	BMD Fn (gr/cm^2)
PHPT (n.30)	0.870±0.15 *	0.750±0.14 *
EH (n.30)	0.980±0.1	0.83±0.11
NS (n.30)	1±0.09	0.82±0.08
𝑃	*<0.001 versus EH-NS	*<0.001 versus EH-NS

BMI: body mass index; WC: waist circumference; SBP: systolic blood pressure; DBP: diastolic blood pressure; HR: heart rate; CT: total cholesterol; LDL-C: low-density cholesterol; HDL-C: high-density cholesterol; TG: triglycerides; ns: not significative; Ca⁺⁺: serum-ionized calcium; Mg⁺⁺: serum-ionized magnesium; Ca Ur: calcium urinary excretion in 24 hours; PTH: serum parathyroid hormone; ALP: serum phosphatase alkaline; BMD: bone mineral density at lumbar spine (L1–L4) and femoral neck (Fn).