Arterial Hypertension, Metabolic Syndrome and Subclinical Cardiovascular Organ Damage in Patients with Asymptomatic Primary Hyperparathyroidism before and after Parathyroidectomy: Preliminary Results

Table 5

Demographic, biochemical, ABPM, echocardiographic, IMT parameters in PHPT patients before (PHPT pre) and after (PHPT post) surgery.

	WC (cm)	SBP (mmHg)	DBP (mmHg)	HR (bpm)	Glycaemia (mg/dL)	CT (mg/dL)	LDL-C (mg/dL)	HDL-C (mg/dL)	TG (mg/dL)
PHPT pre (n.30)	95.7 ± 12	144 ± 19.2	90.4±10.3	75 ± 9.4	92.6±7.5	227 ± 26	146.1 ± 42	54 ± 6.2	135 ± 22
PHPT post (n.30)	95 ± 10.3	117 ± 19.2	83 ± 14.3	65 ± 8.1	87.9±10.2	209 ± 25	132 ± 23	57 ± 12	118 ± 35
P	ns	0.001	0.002	ns	ns	ns	ns	ns	ns
	Calcium (mg/dL)	Ca^++ (mmol/L)	Phosphorous (mg/dL)	Magnesium (mg/dL)	Mg^++ (mmol/L)	Ca Ur (mg/24 h)	P Ur (mg/24 h)	PTH (pg/mL)	ALP (UI/L)
PHPT pre (n.30)	11.2±1.2	1.51±0.2	2.73±0.8	1.94±0.21	0.45±0.06	353±177	829±340	122±47	154±75
PHPT post (n.30)	8.9±2.1	1.2±0.08	3.3±0.76	1.77±0.33	0.51±0.07	126±96	578±277	50.9±22	106±80
P	<0.001	<0.001	<0.001	ns	0.001	<0.001	0.003	<0.001	ns
	SBP-G (mmHg)	DBP-G (mmHg)	HR-G (bpm)	SBP-D (mmHg)	DBP-D (mmHg)	HR-D (bpm)	SBP-N (mmHg)	DBP-N (mmHg)	HR-N (bpm)
PHPT pre (n.30)	126±18	73±21	81±10	130±18	82±10	85±8.5	117±18	67±17	72±8
PHPT post (n.30)	116±18	73±15	75±10	119±15	77±10	77±6.9	109±16	67±16	70±5
P	0.001	ns	0.002	0.001	ns	<0.01	ns	ns	ns
	IVSi (mm/m²)	PWLVi (mm/m²)	LV-DTDi (mm/m²)	LV-DTSi (mm/m²)	LAi (mm/m²)	EF (%)	LVMi (mm/m²)	IMT (mm)
PHPT pre (n.30)	11±0.9	10±1.4	46±5.9	30±2.4	37.5±3.5	59±3.2	182±30	0.8±0.3
PHPT post (n.30)	11±1.2	10±1.1	46±2.2	29.6±3.2	37.5±2.9	56.8±5	176±32	0.7±0.2
P	ns	ns	ns	ns	ns	ns	ns	ns

WC: waist circumference; SBP: systolic blood pressure; DBP: diastolic blood pressure; HR: heart rate; CT: total cholesterol; LDL-C: low-density cholesterol; HDL-C: high-density cholesterol; TG: triglycerides; ns: not significative; Ca⁺⁺: serum-ionized calcium; Mg⁺⁺: serum-ionized magnesium; Ca Ur: calcium urinary excretion in 24 hours; P Ur: phosphorous urinary excretion in 24 hours; PTH: serum parathyroid hormone; ALP: serum phosphatase alkaline; SBP-G: global systolic blood pressure; DBP-G: global diastolic blood pressure; HR-G: global heart rate; SBP-D: diurnal systolic blood pressure; DBP-D: diurnal diastolic blood pressure; HR-D: diurnal heart rate; SBP-N: nocturnal systolic blood pressure; DBP-N: nocturnal diastolic blood pressure; HR-N: nocturnal heart rate; IVSi: interventricle septum; PWLVi: posterior wall; LV-DTDi: telediastolic diameter of left ventricle; LV-DTSi: telesystolic diameter of left ventricle; LAi: left atrium; EF: ejection fraction; LVMi: mass of left ventricle indexed; IMT: intima-media thickness.