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International Journal of Endocrinology
Volume 2012 (2012), Article ID 516718, 20 pages
Review Article

A Simple Matter of Life and Death—The Trials of Postnatal Beta-Cell Mass Regulation

School of Life Sciences, Warwick University, Gibbet Hill Road, Coventry CV4 7AL, UK

Received 15 November 2011; Accepted 31 December 2011

Academic Editor: Velayutham Kumaravel

Copyright © 2012 Elena Tarabra et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [10 citations]

The following is the list of published articles that have cited the current article.

  • Xiao-ye He, Xiao-long Zhao, Qian Gu, Ji-ping Shen, Yu Hu, and Ren-ming Hu, “Calorie Restriction from a Young Age Preserves the Functions of Pancreatic beta Cells in Aging Rats,” Tohoku Journal Of Experimental Medicine, vol. 227, no. 4, pp. 245–252, 2012. View at Publisher · View at Google Scholar
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  • Elizabeth R. Gilbert, and Dongmin Liu, “Anti-diabetic functions of soy isoflavone genistein: mechanisms underlying its effects on pancreatic beta-cell function,” Food & Function, vol. 4, no. 2, pp. 200–212, 2013. View at Publisher · View at Google Scholar
  • Marlon E. Cerf, “Beta cell dynamics: beta cell replenishment, beta cell compensation and diabetes,” Endocrine, vol. 44, no. 2, pp. 303–311, 2013. View at Publisher · View at Google Scholar
  • Lynne L. Levitsky, Goli Ardestani, and David B. Rhoads, “Role of growth factors in control of pancreatic beta cell mass: focus on betatrophin,” Current Opinion in Pediatrics, vol. 26, no. 4, pp. 475–479, 2014. View at Publisher · View at Google Scholar
  • Maria Lindahl, Tatiana Danilova, Erik Palm, Päivi Lindholm, Vootele Võikar, Elina Hakonen, Jarkko Ustinov, Jaan-Olle Andressoo, Brandon K. Harvey, Timo Otonkoski, Jari Rossi, and Mart Saarma, “MANF Is Indispensable for the Proliferation and Survival of Pancreatic β Cells,” Cell Reports, 2014. View at Publisher · View at Google Scholar
  • J. S. Tessem, L. G. Moss, L. C. Chao, M. Arlotto, D. Lu, M. V. Jensen, S. B. Stephens, P. Tontonoz, H. E. Hohmeier, and C. B. Newgard, “Nkx6.1 regulates islet  -cell proliferation via Nr4a1 and Nr4a3 nuclear receptors,” Proceedings of the National Academy of Sciences, vol. 111, no. 14, pp. 5242–5247, 2014. View at Publisher · View at Google Scholar
  • Hidenori Hirukawa, Hideaki Kaneto, Masashi Shimoda, Tomohiko Kimura, Seizo Okauchi, Atsushi Obata, Kenji Kohara, Sumiko Hamamoto, Kazuhito Tawaramoto, Mitsuru Hashiramoto, and Kohei Kaku, “Combination of DPP-4 inhibitor and PPARγ agonist exerts protective effects on pancreatic β-cells in diabetic db/db mice through the augmentation of IRS-2 expression,” Molecular and Cellular Endocrinology, 2015. View at Publisher · View at Google Scholar
  • Eman Ali El-Kordy, and Abdulrahman Mohammed Alshahrani, “Effect of genistein, a natural soy isoflavone, on pancreatic β-cells of streptozotocin-induced diabetic rats: Histological and immunohistochemical study,” Journal of Microscopy and Ultrastructure, 2015. View at Publisher · View at Google Scholar
  • Jason D. Ray, Kyle B. Kener, Benjamin F. Bitner, Brent J. Wright, Matthew S. Ballard, Emily J. Barrett, Jonathon T. Hill, Larry G. Moss, and Jeffery S. Tessem, “Nkx6.1-mediated insulin secretion and β-cell proliferation is dependent on upregulation of c-Fos,” FEBS Letters, vol. 590, no. 12, pp. 1791–1803, 2016. View at Publisher · View at Google Scholar