Compromised Rat Testicular Antioxidant Defence System by Hypothyroidism before Puberty

Table 3

Effect of neonatal PTU treatment on serum total T₃, total T₄, testosterone levels (ng/mL), and thyroid stimulating hormone (TSH) level in μIU/mL). Data are expressed as mean ± S.D. of 5 observations and subjected to unpaired Student’s t-test. Statistical significance was accepted at 𝑃<0.05. Control and hypothyroid groups were found to differ significantly at 𝑃<0.05 as represented by superscripts of different letters. Group-I (control): 30-day-old control rats; Group-II (hypothyroid): 30-day-old rats with PTU treatment from day 1 postpartum to day 30 postpartum.

Serum hormones	Group-I (control)	Group-II (hypothyroid)
Total T3 (ng/mL)	1.68 ± 0.16^a	1.02 ± 0.08^b
Total T4 (ng/mL)	13.00 ± 3.92^a	3.00 ± 0.61^b
TSH (μIU/mL)	0.12 ± 0.027^a	1.69 ± 0.089^b
Testosterone (ng/mL)	0.25 ± 0.03^a	0.09 ± 0.02^b