Interactions between Serum Adipokines and Osteocalcin in Older Patients with Hip Fracture

Table 2

Associations of serum leptin, adiponectin, and resistin with serum osteocalcin as dependent variable in linear regression models.

Adjustments	Leptin		Adiponectin		Resistin
	β	P	β	𝑃	β	𝑃
Unadjusted	0.071	0.038	−0.015	0.859	−0.064	0.372
^+Age, sex, BMI	0.093	0.008	−0.087	0.329	−0.099	0.167
^+HF type	0.093	0.009	−0.084	0.350	−0.097	0.182
^+25(OH)D	0.081	0.023	−0.126	.0162	−0.138	0.055
^+PTH	0.080	0.024	−0.138	0.129	−0.169	0.022
^+Ca, Mg, PO4	0.079	0.027	−0.123	0.072	−0.178	0.019
^+eGFR	0.055	0.105	−0.073	0.406	−0.162	0.026
^+Haemoglobin	0.076	0.046	−0.075	0.394	−0.162	0.026
^+Two other adipokines	0.077	0.040	−0.051	0.567	−0.173	0.018
^+Type 2 DM	0.090	0.018	−0.053	0.551	−0.119	0.126
^+Hypertension*	0.078	0.046	−0.055	0.544	−0.173	0.021
^+CVD (any)*	0.090	0.023	−0.059	0.575	−0.156	0.037
^+CVD (any)	0.099	0.014	−0.061	0.507	−0.104	0.191

Leptin, adiponectin, resistin, and osteocalcin were included in models as logarithmically transformed variables; ⁺indicates adjustments for all covariates in the above model; *indicates adjustments for all covariates in the above model except type 2 DM; β standard regression coefficient; P probability value; DM, diabetes mellitus; CVD, cardiovascular disease; BMI, body mass index; HF, hip fracture; 25(OH)D, 25 hydroxy vitamin D; PTH, parathyroid hormone; Ca, calcium; Mg, magnesium; PO₄, phosphate; eGFR, estimated glomerular filtration rate.