Clinical Study
Adjunctive Sitagliptin Therapy in Postoperative Cardiac Surgery Patients: A Pilot Study
Table 3
Antihyperglycemic medication utilization.
| Variable | Sitagliptin () | Placebo () | value |
| Overall insulin utilization | | | | Mean number of units over 4-day study period, | 13.2 ± 13.5 | 13.5 ± 12.6 | 0.942 | Mean amount of dextrose utilized during study*, grams | 4.8 ± 6.3 | 3.4 ± 3.4 | 0.307 | Insulin utilization SD no. 1 | | | | Mean number of units, | 32.5 ± 26.5 | 34.0 ± 36.5 | 0.857 | Mean amount of dextrose, grams | 13.7 ± 11.2 | 7.0 ± 7.5 | 0.008 | Insulin utilization SD no. 2 | | | | Mean number of units, | 10.1 ± 15.7 | 7.2 ± 11.5 | 0.411 | Mean amount of dextrose, grams | 1.4 ± 4.4 | 2.6 ± 7.0 | 0.437 | Insulin utilization SD no. 3 | | | | Mean number of units, | 6.3 ± 12.1 | 4.5 ± 8.3 | 0.500 | Mean amount of dextrose, grams | 1.5 ± 6.6 | 1.3 ± 4.1 | 0.917 | Insulin utilization SD no. 4 | | | | Mean number of units, | 5.7 ± 11.8 | 3.1 ± 5.2 | 0.319 | Mean amount of dextrose, grams | 1.4 ± 6.8 | 0.6 ± 1.6 | 0.593 | Oral Agents | | | | Percentage of subjects with home medications restarted SD no. 1 | 53.3% | 34.4% | 0.212 | Percentage of subjects with home medications restarted SD no. 2 | 70% | 50% | 0.179 | Percentage of subjects with home medications restarted SD no. 3 | 70% | 59.4% | 0.543 | Percentage of subjects with home medications restarted SD no. 4 | 70% | 65.6% | 0.923 |
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*Amount of dextrose infused in medications and/or continuous infusions. SD: study day.
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