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International Journal of Endocrinology
Volume 2012, Article ID 879134, 8 pages
Research Article

Markers of Sleep Disordered Breathing and Diabetes Mellitus in a Multiethnic Sample of US Adults: Results from the National Health and Nutrition Examination Survey (2005–2008)

1Department of Community Medicine, West Virginia University School of Medicine, Robert C. Byrd Health Sciences Center, Medical Center Drive, P.O. Box 9190, Morgantown, WV 26505-9190, USA
2Singapore Eye Research Institute, Singapore National Eye Center, 11 Third Hospital Avenue, No. 05-00, Singapore 168751

Received 31 May 2011; Revised 23 September 2011; Accepted 25 October 2011

Academic Editor: D. S. Jessop

Copyright © 2012 Charumathi Sabanayagam et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


We examined gender and ethnic differences in the association between sleep disordered breathing (SDB) and diabetes among 6,522 participants aged ≥20 years from the National Health and Nutrition Examination Survey 2005–08. SDB severity was defined based on an additive summary score including sleep duration, snoring, snorting, and daytime sleepiness. We found that the summary SDB score was significantly associated with diabetes after adjusting for potential confounders in the whole population. Compared to those without any sleep disturbance, the multivariable odds ratio (OR) (95% confidence interval (CI)) of diabetes among those with ≥3 sleep disturbances was 2.04 (1.46–2.87). In sex-specific analyses, this association was significant only in women (OR (95% CI) = 3.68 (2.01–6.72)) but not in men (1.10 (0.59–2.04)), -interaction . However, there were no ethnic differences in this association, -interaction . In a nationally representative sample of US adults, SDB was independently associated with diabetes only in women, but not in men.