Table 1: Adult patients in whom testing for GHD can be considered.

(i) Those with structural lesions of hypothalamic-pituitary region for example, pituitary adenoma, craniopharyngioma
(ii) Following surgery to the hypothalamic-pituitary region
(iii) Those with biochemical evidence of hypopituitarism for example, central hypothyroidism
(iv) Those with genetic conditions associated with hypopituitarism for example, PIT-1, PROP-1 mutations
(v) Following cranial irradiation
(vi) Following moderate to severe traumatic brain injury and possibly aneurysmal subarachnoid haemorrhage