Comparison of Insulin Lispro Protamine Suspension with NPH Insulin in Pregnant Women with Type 2 and Gestational Diabetes Mellitus: Maternal and Perinatal Outcomes
Table 4
Insulin need (units/kg/day) at the end of pregnancy in women receiving ILPS or NPH insulin.
ILPSg ( = 53)
NPHg ( = 36)
Total insulin
Total
0.36 0.27
0.58 0.20
<0.0001
T2DM
0.50 0.22
0.68 0.18
<0.05
GDM
0.34 0.28
0.48 0.19
<0.05
Short-acting insulin analogue
Total
0.30 0.18
0.44 0.17
0.001
T2DM
0.33 0.13
0.50 0.14
0.01
GDM
0.30 0.19
0.38 0.18
ns
Intermediate-acting insulin
Total
0.12 0.10
0.14 0.07
ns
T2DM
0.18 0.07
0.17 0.07
ns
GDM
0.11 0.09
0.11 0.06
ns
T2DM: type 2 diabetes mellitus; GDM: gestational diabetes mellitus.
