International Journal of Endocrinology / 2013 / Article / Fig 2

Review Article

The Endocannabinoid System and Sex Steroid Hormone-Dependent Cancers

Figure 2

Synthesis of 2-AG. Phosphatidylinositol-4,5-bisphosphate (PIP2) is hydrolysed by phospholipase C-β (PLC-β) to form diacylglycerol (DAG). The DAG is then hydrolysed to 2-AG by diacylglycerol lipase (DAGL).

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